Jonathan C Trinidad
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Explore the profile of Jonathan C Trinidad including associated specialties, affiliations and a list of published articles.
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81
Citations
3271
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Recent Articles
11.
Jordan M, Gonzalez-Gutierrez G, Trinidad J, Giedroc D
Proc Natl Acad Sci U S A
. 2022 Nov;
119(49):e2213630119.
PMID: 36442121
In response to bacterial infection, the vertebrate host employs the metal-sequestering protein calprotectin (CP) to withhold essential transition metals, notably Zn(II), to inhibit bacterial growth. Previous studies of the impact...
12.
Dixon A, Robson S, Trinidad J, Ziarek J
Protein Sci
. 2022 Sep;
31(11):e4454.
PMID: 36116099
Fluorine ( F) offers several distinct advantages for biomolecular nuclear magnetic resonance spectroscopy such as no background signal, 100% natural abundance, high sensitivity, and a large chemical shift range. Exogenous...
13.
Munley K, Trinidad J, Demas G
Proc Biol Sci
. 2022 Sep;
289(1982):20220668.
PMID: 36100021
Coordinating physiological and behavioural processes across the annual cycle is essential in enabling individuals to maximize fitness. While the mechanisms underlying seasonal reproduction and its associated behaviours are well characterized,...
14.
Walsh B, Costa S, Edmonds K, Trinidad J, Issoglio F, Brito J, et al.
Antioxidants (Basel)
. 2022 Aug;
11(8).
PMID: 36009332
Hydrogen sulfide (HS) is implicated as a cytoprotective agent that bacteria employ in response to host-induced stressors, such as oxidative stress and antibiotics. The physiological benefits often attributed to HS,...
15.
Brown B, Guda P, Zeng X, Anthony A, Couse A, Barnes L, et al.
Anal Chem
. 2022 Jun;
94(25):8909-8918.
PMID: 35699514
Unresolved inflammation compromises diabetic wound healing. Recently, we reported that inadequate RNA packaging in murine wound-edge keratinocyte-originated exosomes () leads to persistent inflammation [Zhou, X. 2020, 14(10), 12732-12748]. Herein, we...
16.
Dixon A, Inoue A, Robson S, Culhane K, Trinidad J, Sivaramakrishnan S, et al.
J Am Chem Soc
. 2022 Jun;
144(23):10241-10250.
PMID: 35647863
Using a discrete, intracellular F nuclear magnetic resonance (NMR) probe on transmembrane helix 6 of the neurotensin receptor 1 (NTS1), we aim to understand how ligands and transducers modulate the...
17.
Gavade J, Puccia C, Herod S, Trinidad J, Berchowitz L, Lacefield S
Curr Biol
. 2022 Mar;
32(7):1534-1547.e9.
PMID: 35240051
The initiation of the cell division process of meiosis requires exogenous signals that activate internal gene regulatory networks. Meiotic commitment ensures the irreversible continuation of meiosis, even upon withdrawal of...
18.
Zeng X, Novotny M, Clemmer D, Trinidad J
Glycobiology
. 2021 Dec;
32(3):201-207.
PMID: 34939082
A substantial shortcoming of large-scale datasets is often the inability to easily represent and visualize key features. This problem becomes acute when considering the increasing technical ability to profile large...
19.
Yu X, Martin P, Zhang Y, Trinidad J, Xu F, Huang J, et al.
Curr Biol
. 2021 Oct;
31(23):5377-5384.e5.
PMID: 34666004
Transcription initiation has long been considered a primary regulatory step in gene expression. Recent work, however, shows that downstream events, such as transcription elongation, can also play important roles. A...
20.
El-Baba T, Raab S, Buckley R, Brown C, Lutomski C, Henderson L, et al.
Anal Chem
. 2021 Jun;
93(24):8484-8492.
PMID: 34101419
The thermal stabilities of endogenous, intact proteins and protein assemblies in complex mixtures were characterized in parallel by means of variable-temperature electrospray ionization coupled to mass spectrometry (vT-ESI-MS). The method...