Jonathan Barasch
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Explore the profile of Jonathan Barasch including associated specialties, affiliations and a list of published articles.
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99
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8327
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Recent Articles
1.
Manrique-Caballero C, Barasch J, Zaidi S, Bates C, Ray E, Kleyman T, et al.
Am J Physiol Renal Physiol
. 2024 Nov;
328(1):F107-F120.
PMID: 39588770
Mucin 1 (or MUC1) is a heterodimeric transmembrane glycoprotein expressed on the apical surface of polarized epithelial cells in several tissues including the kidney. Recent studies have revealed several novel...
2.
Beenken A, Shen T, Jin G, Ghotra A, Xu K, Nesanir K, et al.
Am J Physiol Renal Physiol
. 2024 Sep;
327(5):F775-F787.
PMID: 39265081
Proximal tubule endocytosis is essential to produce protein-free urine as well as to regulate system-wide metabolic pathways, such as the activation of Vitamin D. We have determined that the proximal...
3.
Schmidt I, Surapaneni A, Zhao R, Upadhyay D, Yeo W, Schlosser P, et al.
Nat Commun
. 2024 Aug;
15(1):7368.
PMID: 39191768
The kidney tubules constitute two-thirds of the cells of the kidney and account for the majority of the organ's metabolic energy expenditure. Acute tubular injury (ATI) is observed across various...
4.
Hinze C, Lovric S, Halloran P, Barasch J, Schmidt-Ott K
Nat Rev Nephrol
. 2024 Apr;
20(7):447-459.
PMID: 38632381
The kidney epithelium, with its intricate arrangement of highly specialized cell types, constitutes the functional core of the organ. Loss of kidney epithelium is linked to the loss of functional...
5.
Steers N, Barasch J
Kidney Int
. 2023 Jul;
104(2):236-238.
PMID: 37479384
Like most epithelial organs, the bladder and kidney can be directly accessed by bacteria evolved for invasion. Epithelia and immune cells attempt to stymie this infection with biophysical and chemical...
6.
Cardenas-Diaz F, Liberti D, Leach J, Babu A, Barasch J, Shen T, et al.
Cell Rep
. 2023 Apr;
42(5):112451.
PMID: 37119134
Alveolar epithelial type 2 (AT2) cells harbor the facultative progenitor capacity in the lung alveolus to drive regeneration after lung injury. Using single-cell transcriptomics, software-guided segmentation of tissue damage, and...
7.
Beenken A, Cerutti G, Brasch J, Guo Y, Sheng Z, Erdjument-Bromage H, et al.
Cell
. 2023 Feb;
186(4):821-836.e13.
PMID: 36750096
The low-density lipoprotein (LDL) receptor-related protein 2 (LRP2 or megalin) is representative of the phylogenetically conserved subfamily of giant LDL receptor-related proteins, which function in endocytosis and are implicated in...
8.
Shen T, Stauber J, Xu K, Jacunski A, Paragas N, Callahan M, et al.
JCI Insight
. 2022 Mar;
7(6).
PMID: 35230973
The current strategy to detect acute injury of kidney tubular cells relies on changes in serum levels of creatinine. Yet serum creatinine (sCr) is a marker of both functional and...
9.
Munoz J, Uhlemann A, Barasch J
Annu Rev Physiol
. 2021 Nov;
84:533-558.
PMID: 34780258
Urinary tract infection (UTI) is the most common type of urogenital disease. UTI affects the urethra, bladder, ureter, and kidney. A total of 13.3% of women, 2.3% of men, and...
10.
Kudose S, Santoriello D, Bomback A, Sekulic M, Batal I, Stokes M, et al.
J Am Soc Nephrol
. 2021 Oct;
32(11):2958-2969.
PMID: 34670811
Background: The long-term outcome of COVID-19-associated collapsing glomerulopathy is unknown. Methods: We retrospectively identified 76 native kidney biopsies from patients with history of COVID-19 between March 2020 and April 2021....