Jonathan B Chaires
Overview
Explore the profile of Jonathan B Chaires including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
107
Citations
2556
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Monsen R, Sabo T, Gray R, Hopkins J, Chaires J
Nucleic Acids Res
. 2025 Jan;
53(3).
PMID: 39883009
Time-resolved small-angle X-ray experiments are reported here that capture and quantify a previously unknown rapid collapse of the unfolded oligonucleotide as an early step in the folding of hybrid 1...
2.
Schneider G, Kaliappan A, Joos N, Dooley L, Shumway B, Chaires J, et al.
Cancers (Basel)
. 2025 Jan;
16(24.
PMID: 39766119
Background: Over the past decade, saliva-based liquid biopsies have emerged as promising tools for the early diagnosis, prognosis, and monitoring of cancer, particularly in high-risk populations. However, challenges persist because...
3.
Seth P, Xing E, Hendrickson A, Li K, Monsen R, Chaires J, et al.
Nucleic Acids Res
. 2024 Dec;
53(2.
PMID: 39704129
Left-handed G-quadruplexes (LHG4s) belong to a class of recently discovered noncanonical DNA structures under the larger umbrella of G-quadruplex DNAs (G4s). The biological relevance of these structures and their ability...
4.
Monsen R, Sabo T, Gray R, Hopkins J, Chaires J
bioRxiv
. 2024 Sep;
PMID: 39282441
Time-resolved small-angle X-ray experiments (TR-SAXS) are reported here that capture and quantify a previously unknown rapid collapse of the unfolded oligonucleotide as an early step in G4 folding of hybrid...
5.
Salsbury Jr F, Adnan M, Bishop T, Chaires J, Hassan M
J Biomol Struct Dyn
. 2024 Aug;
:1-2.
PMID: 39114878
No abstract available.
6.
Sabo T, Trent J, Chaires J, Monsen R
Methods
. 2024 Jul;
230:9-20.
PMID: 39032720
Guanine-rich nucleic acids can form intramolecularly folded four-stranded structures known as G-quadruplexes (G4s). Traditionally, G4 research has focused on short, highly modified DNA or RNA sequences that form well-defined homogeneous...
7.
Chakraborty G, Balinin K, Villar-Guerra R, Emondts M, Portale G, Loznik M, et al.
iScience
. 2024 May;
27(5):109689.
PMID: 38706840
The distinct folding accompanied by its polymorphic character renders DNA G-quadruplexes promising biomolecular building blocks to construct novel DNA-based and supramolecular assemblies. However, the highly polar nature of DNA limits...
8.
Monsen R, Chua E, Hopkins J, Chaires J, Trent J
Nucleic Acids Res
. 2023 Jan;
51(4):1943-1959.
PMID: 36715343
Genomic regions with high guanine content can fold into non-B form DNA four-stranded structures known as G-quadruplexes (G4s). Extensive in vivo investigations have revealed that promoter G4s are transcriptional regulators....
9.
Monsen R, Trent J, Chaires J
Acc Chem Res
. 2022 Oct;
55(22):3242-3252.
PMID: 36282946
G-quadruplexes (G4s) are distinctive four-stranded DNA or RNA structures found within cells that are thought to play functional roles in gene regulation and transcription, translation, recombination, and DNA damage/repair. While...
10.
Monsen R, Maguire J, DeLeeuw L, Chaires J, Trent J
PLoS One
. 2022 Jun;
17(6):e0270165.
PMID: 35709230
DNA G-quadruplexes (G4s) are now widely accepted as viable targets in the pursuit of anticancer therapeutics. To date, few small molecules have been identified that exhibit selectivity for G4s over...