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Jonas Fischer

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Articles 26
Citations 135
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Recent Articles
1.
Keller S, Fischer J, Ji S, Zwingmann L, Wahl P
Int J Sports Med . 2025 Mar; PMID: 40032263
The study investigated 1.The agreement of modeled lactate threshold 2 (LT2) using maximal oxygen uptake (V̇O),cost of locomotion (C), and fractional utilization of (V̇O) at LT2 (LT2) with maximal lactate...
2.
Fischer J, Szabo B, Manikhin L, Filser J
Environ Toxicol Chem . 2025 Feb; PMID: 39999022
Soils are exposed to multiple substance groups, including surfactants, which directly enter soils when they are used as additives in fire-fighting liquids or pesticide mixtures due to their surface tension-lowering...
3.
Chen C, Saha E, Fischer J, Ben Guebila M, Fanfani V, Shutta K, et al.
bioRxiv . 2025 Feb; PMID: 39975108
Lung adenocarcinoma (LUAD) exhibits differences between the sexes in incidence, prognosis, and therapy, suggesting underexplored molecular mechanisms. We conducted an integrative multi-omics analysis using the Clinical Proteomic Tumor Analysis Consortium...
4.
Fanfani V, Shutta K, Mandros P, Fischer J, Saha E, Micheletti S, et al.
bioRxiv . 2024 Nov; PMID: 39574772
Background: Technological advances in sequencing and computation have allowed deep exploration of the molecular basis of diseases. Biological networks have proven to be a useful framework for interrogating omics data...
5.
Hartmann C, Khan R, Schoning J, Richter M, Willers M, Pirr S, et al.
Front Immunol . 2024 Oct; 15:1443665. PMID: 39355253
Introduction: Respiratory viral infections (RVIs) are a major global contributor to morbidity and mortality. The susceptibility and outcome of RVIs are strongly age-dependent and show considerable inter-population differences, pointing to...
6.
Fischer J, Shutta K, Chen C, Fanfani V, Saha E, Mandros P, et al.
bioRxiv . 2024 Sep; PMID: 39345481
There is increasing recognition that the sex chromosomes, X and Y, play an important role in health and disease that goes beyond the determination of biological sex. Loss of the...
7.
Saha E, Fanfani V, Mandros P, Ben Guebila M, Fischer J, Shutta K, et al.
Genome Res . 2024 Aug; 34(9):1397-1410. PMID: 39134413
Gene regulatory networks (GRNs) are effective tools for inferring complex interactions between molecules that regulate biological processes and hence can provide insights into drivers of biological systems. Inferring coexpression networks...
8.
Saha E, Ben Guebila M, Fanfani V, Fischer J, Shutta K, Mandros P, et al.
Biol Sex Differ . 2024 Aug; 15(1):62. PMID: 39107837
Background: Lung adenocarcinoma (LUAD) has been observed to have significant sex differences in incidence, prognosis, and response to therapy. However, the molecular mechanisms responsible for these disparities have not been...
9.
Dirks J, Fischer J, Klaussner J, Hofmann C, Holl-Wieden A, Buck V, et al.
J Clin Invest . 2024 Jul; 134(17). PMID: 38963700
BACKGROUNDAntibiotic-Refractory Lyme Arthritis (ARLA) involves a complex interplay of T cell responses targeting Borrelia burgdorferi antigens progressing toward autoantigens by epitope spreading. However, the precise molecular mechanisms driving the pathogenic...
10.
Mandros P, Gallagher I, Fanfani V, Chen C, Fischer J, Ismail A, et al.
bioRxiv . 2024 Jul; PMID: 38948759
Computational methods in biology can infer large molecular interaction networks from multiple data sources and at different resolutions, creating unprecedented opportunities to explore the mechanisms driving complex biological phenomena. Networks...