Jonas D van Belleghem
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Explore the profile of Jonas D van Belleghem including associated specialties, affiliations and a list of published articles.
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17
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903
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Recent Articles
1.
Dharmaraj T, Kratochvil M, Pourtois J, Chen Q, Hajfathalian M, Hargil A, et al.
PNAS Nexus
. 2023 Dec;
2(12):pgad406.
PMID: 38111822
Extensive efforts are underway to develop bacteriophages as therapies against antibiotic-resistant bacteria. However, these efforts are confounded by the instability of phage preparations and a lack of suitable tools to...
2.
Dharmaraj T, Kratochvil M, Pourtois J, Chen Q, Hajfathalian M, Hargil A, et al.
bioRxiv
. 2023 Jul;
PMID: 37425882
Extensive efforts are underway to develop bacteriophages as therapies against antibiotic-resistant bacteria. However, these efforts are confounded by the instability of phage preparations and a lack of suitable tools to...
3.
Bach M, de Vries C, Khosravi A, Sweere J, Popescu M, Chen Q, et al.
Cell Rep Med
. 2022 Jun;
3(6):100656.
PMID: 35732145
Chronic wounds infected by Pseudomonas aeruginosa (Pa) are characterized by disease progression and increased mortality. We reveal Pf, a bacteriophage produced by Pa that delays healing of chronically infected wounds...
4.
Liu D, van Belleghem J, de Vries C, Burgener E, Chen Q, Manasherob R, et al.
Viruses
. 2021 Jul;
13(7).
PMID: 34209836
Increasing rates of infection by antibiotic resistant bacteria have led to a resurgence of interest in bacteriophage (phage) therapy. Several phage therapy studies in animals and humans have been completed...
5.
Popescu M, van Belleghem J, Khosravi A, Bollyky P
Annu Rev Virol
. 2021 May;
8(1):415-435.
PMID: 34014761
Bacteriophages-viruses that infect bacteria-are abundant within our bodies, but their significance to human health is only beginning to be explored. Here, we synthesize what is currently known about our phageome...
6.
van Belleghem J, Manasherob R, Midzybrodzki R, Rogoz P, Gorski A, Suh G, et al.
Front Microbiol
. 2021 Jan;
11:591021.
PMID: 33408703
Prosthetic joint infection (PJI) is a devastating complication after a joint replacement. PJI and its treatment have a high monetary cost, morbidity, and mortality. The lack of success treating PJI...
7.
de Vries C, Chen Q, Demirdjian S, Kaber G, Khosravi A, Liu D, et al.
Curr Opin Biotechnol
. 2020 Dec;
68:160-165.
PMID: 33316575
Bacteriophages have attracted extensive interest in vaccine design. This includes the use of phage display technology to select antigens, the use of engineered phages displaying target antigens in vaccine formulations,...
8.
Cano E, Caflisch K, Bollyky P, van Belleghem J, Patel R, Fackler J, et al.
Clin Infect Dis
. 2020 Jul;
73(1):e144-e151.
PMID: 32699879
Background: Prosthetic joint infection (PJI) is a potentially limb-threatening complication of total knee arthroplasty. Phage therapy is a promising strategy to manage such infections including those involving antibiotic-resistant microbes, and...
9.
Secor P, Burgener E, Kinnersley M, Jennings L, Roman-Cruz V, Popescu M, et al.
Front Immunol
. 2020 Mar;
11:244.
PMID: 32153575
Pf bacteriophage are temperate phages that infect the bacterium , a major cause of chronic lung infections in cystic fibrosis (CF) and other settings. Pf and other temperate phages have...
10.
Koliesnik I, Kuipers H, Medina C, Zihsler S, Liu D, van Belleghem J, et al.
Front Immunol
. 2020 Mar;
11:132.
PMID: 32117279
The heparan sulfate mimetic PG545 (pixatimod) is under evaluation as an inhibitor of angiogenesis and metastasis including in human clinical trials. We have examined the effects of PG545 on lymphocyte...