Jonas Beal
Overview
Explore the profile of Jonas Beal including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
95
Followers
0
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Recent Articles
1.
Lopez-Herdoiza M, Bauche S, Wilmet B, Le Duigou C, Roussel D, Frah M, et al.
Front Cell Neurosci
. 2023 May;
17:1155929.
PMID: 37138765
The GGGGCC intronic repeat expansion within is the most common genetic cause of ALS and FTD. This mutation results in toxic gain of function through accumulation of expanded RNA foci...
2.
Montagud A, Beal J, Tobalina L, Traynard P, Subramanian V, Szalai B, et al.
Elife
. 2022 Feb;
11.
PMID: 35164900
Prostate cancer is the second most occurring cancer in men worldwide. To better understand the mechanisms of tumorigenesis and possible treatment responses, we developed a mathematical model of prostate cancer...
3.
Beal J, Pantolini L, Noel V, Barillot E, Calzone L
PLoS Comput Biol
. 2021 Jan;
17(1):e1007900.
PMID: 33507915
The study of response to cancer treatments has benefited greatly from the contribution of different omics data but their interpretation is sometimes difficult. Some mathematical models based on prior biological...
4.
Scholl S, Beal J, De Koning L, Girard E, Popovic M, De la Rochefordiere A, et al.
EBioMedicine
. 2020 Oct;
61:103049.
PMID: 33096476
Background: Cervical cancer (CC) remains a leading cause of gynaecological cancer-related mortality world wide and constitutes the third most common malignancy in women. The RAIDs consortium (http://www.raids-fp7.eu/) conducted a prospective...
5.
Miskovic L, Beal J, Moret M, Hatzimanikatis V
PLoS Comput Biol
. 2019 Aug;
15(8):e1007242.
PMID: 31430276
A persistent obstacle for constructing kinetic models of metabolism is uncertainty in the kinetic properties of enzymes. Currently, available methods for building kinetic models can cope indirectly with uncertainties by...
6.
Beal J, Montagud A, Traynard P, Barillot E, Calzone L
Front Physiol
. 2019 Feb;
9:1965.
PMID: 30733688
Logical models of cancer pathways are typically built by mining the literature for relevant experimental observations. They are usually generic as they apply for large cohorts of individuals. As a...