Jon A Harper
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Explore the profile of Jon A Harper including associated specialties, affiliations and a list of published articles.
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2
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Recent Articles
1.
Crawford M, Harper J, Cooper T, Marsolier-Kergoat M, Llorente B, Neale M
PLoS Genet
. 2024 Dec;
20(12):e1011485.
PMID: 39652586
During meiosis, programmed DNA double-strand breaks (DSBs) are formed by the topoisomerase-like enzyme, Spo11, activating the DNA damage response (DDR) kinase Mec1ATR via the checkpoint clamp loader, Rad24RAD17. At single...
2.
Johnson D, Allison R, Cannavo E, Cejka P, Harper J, Neale M
DNA Repair (Amst)
. 2024 Sep;
142:103757.
PMID: 39236418
Meiotic recombination is initiated by DNA double-strand breaks (DSBs) created by Spo11, a type-II topoisomerase-like protein that becomes covalently linked to DSB ends. Whilst Spo11 oligos-the products of nucleolytic removal...