Bertrand Llorente
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Explore the profile of Bertrand Llorente including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
1326
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Recent Articles
1.
Crawford M, Harper J, Cooper T, Marsolier-Kergoat M, Llorente B, Neale M
PLoS Genet
. 2024 Dec;
20(12):e1011485.
PMID: 39652586
During meiosis, programmed DNA double-strand breaks (DSBs) are formed by the topoisomerase-like enzyme, Spo11, activating the DNA damage response (DDR) kinase Mec1ATR via the checkpoint clamp loader, Rad24RAD17. At single...
2.
Dutta A, Dutreux F, Garin M, Caradec C, Friedrich A, Brach G, et al.
PLoS Genet
. 2024 Sep;
20(9):e1011426.
PMID: 39325820
Meiotic recombination is essential for the accurate chromosome segregation and the generation of genetic diversity through crossover and gene conversion events. Although this process has been studied extensively in a...
3.
Legrand S, Saifudeen A, Bordelet H, Vernerey J, Guille A, Bignaud A, et al.
Proc Natl Acad Sci U S A
. 2024 Mar;
121(12):e2312820121.
PMID: 38478689
Meiotic recombination shows broad variations across species and along chromosomes and is often suppressed at and around genomic regions determining sexual compatibility such as mating type loci in fungi. Here,...
4.
Lian Q, Maestroni L, Gaudin M, Llorente B, Mercier R
iScience
. 2023 Sep;
26(9):107614.
PMID: 37664590
In most eukaryotes, meiotic crossovers (COs) are limited to 1-3 per chromosome, and are prevented from occurring close to one another by CO interference. The fission yeast , an exception...
5.
Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii
Dutreux F, Dutta A, Peltier E, Bibi-Triki S, Friedrich A, Llorente B, et al.
PLoS Genet
. 2023 Jan;
19(1):e1010592.
PMID: 36608114
Meiotic recombination is a driving force for genome evolution, deeply characterized in a few model species, notably in the budding yeast Saccharomyces cerevisiae. Interestingly, Zip2, Zip3, Zip4, Spo16, Msh4, and...
6.
Uribe-Calvillo T, Maestroni L, Marsolier M, Khadaroo B, Arbiol C, Schott J, et al.
PLoS Genet
. 2022 Jun;
18(6):e1010124.
PMID: 35727827
Break-induced replication (BIR) is a highly mutagenic eukaryotic homologous DNA recombination pathway that repairs one-ended DNA double strand breaks such as broken DNA replication forks and eroded telomeres. While searching...
7.
Li J, Llorente B, Liti G, Yue J
PLoS Genet
. 2022 May;
18(5):e1010047.
PMID: 35533184
Meiotic recombination is an essential biological process that ensures faithful chromosome segregation and promotes parental allele shuffling. Tetrad analysis is a powerful approach to quantify the genetic makeups and recombination...
8.
Peltier E, Bibi-Triki S, Dutreux F, Caradec C, Friedrich A, Llorente B, et al.
G3 (Bethesda)
. 2021 Sep;
11(9).
PMID: 34544138
Dissecting the genetic basis of complex trait remains a real challenge. The budding yeast Saccharomyces cerevisiae has become a model organism for studying quantitative traits, successfully increasing our knowledge in...
9.
Johnson D, Crawford M, Cooper T, Claeys Bouuaert C, Keeney S, Llorente B, et al.
Nature
. 2021 Jun;
594(7864):572-576.
PMID: 34108687
Genetic recombination arises during meiosis through the repair of DNA double-strand breaks (DSBs) that are created by Spo11, a topoisomerase-like protein. Spo11 DSBs form preferentially in nucleosome-depleted regions termed hotspots,...
10.
Vernekar D, Reginato G, Adam C, Ranjha L, Dingli F, Marsolier M, et al.
Nucleic Acids Res
. 2021 Apr;
49(8):4522-4533.
PMID: 33823531
Meiotic recombination ensures proper chromosome segregation to form viable gametes and results in gene conversions events between homologs. Conversion tracts are shorter in meiosis than in mitotically dividing cells. This...