Johnny Cheuk-On Tang
Overview
Explore the profile of Johnny Cheuk-On Tang including associated specialties, affiliations and a list of published articles.
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23
Citations
258
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Recent Articles
1.
Tang J, Chan D, Chung P, Liu Y, Lam A, Law S, et al.
Int J Mol Med
. 2024 Oct;
54(6).
PMID: 39364750
Esophageal squamous cell carcinoma (ESCC) is a particularly aggressive form of cancer with high mortality. In the present study, a novel 8‑hydroxyquinoline derivative (91b1) was investigated for its anticancer activities...
2.
Zhou Z, Tao C, Li J, Tang J, Chan A, Zhou Y
Front Immunol
. 2022 Nov;
13:984864.
PMID: 36389701
Chimeric antigen receptor T cell (CAR-T) therapy is novel tumor immunotherapy that enables autologous T to express synthetic receptors to specifically recognize the surface tumor-associated antigens for exerting subsequent antitumor...
3.
Zhou Y, Chung P, Ma J, Lam A, Law S, Chan K, et al.
Biology (Basel)
. 2019 Oct;
8(4).
PMID: 31581572
Multidrug resistance (MDR) is one of conventional cancer chemotherapy's limitations. Our group previously synthesized a series of quinoline-based compounds in an attempt to identify novel anticancer agents. With a molecular...
4.
Lee K, Vider J, Tang J, Gopalan V, Lam A
Mol Carcinog
. 2019 Mar;
58(7):1145-1154.
PMID: 30825264
Gene amplified in esophageal cancer 1 (GAEC1) expression and copy number changes are frequently associated with the pathogenesis of colorectal carcinomas. The current study aimed to identify the pathway and...
5.
Islam F, Gopalan V, Law S, Tang J, Lam A
Hum Pathol
. 2019 Feb;
87:1-10.
PMID: 30794892
Family with sequence similarity 134, member B (FAM134B) is an autophagy regulator of endoplasmic reticulum first discovered to be involved in the pathogenesis of esophageal squamous cell carcinoma (ESCC). The...
6.
Chung P, Lam P, Zhou Y, Gasparello J, Finotti A, Chilin A, et al.
Cells
. 2018 Oct;
7(10).
PMID: 30360426
Quinoline core has been shown to possess a promising role in the development of anticancer agents. However, the correlation between its broad spectrum of bioactivity and the underlying mechanism of...
7.
An B, Zhang S, Hu J, Pan T, Huang L, Tang J, et al.
Org Biomol Chem
. 2018 Jun;
16(25):4701-4714.
PMID: 29900452
Inhibition of tubulin polymerization is one of the significant strategies in the treatment of cancer. Inspired by the excellent antitumor activity of EP128495 and the beneficial biological activities of selenium...
8.
Islam F, Gopalan V, Law S, Tang J, Chan K, Lam A
Hum Pathol
. 2017 Feb;
62:141-151.
PMID: 28188753
MicroRNA-498 plays a crucial role in progression of many carcinomas. The signaling pathways by which miR-498 modulates carcinogenesis are still unknown. Also, miR-498-associated molecular pathogenesis has never been studied in...
9.
Gopalan V, Islam F, Pillai S, Tang J, Tong D, Law S, et al.
Exp Cell Res
. 2016 Sep;
348(2):146-154.
PMID: 27658568
Purpose: This study aims to examine the expression profiles miR-1288 in oesophageal squamous cell carcinoma (ESCC). The cellular implications and target interactions of ESCC cells following miR-1288 overexpression was also...
10.
Chung P, Bian Z, Pun H, Chan D, Chan A, Chui C, et al.
Future Med Chem
. 2015 Jun;
7(7):947-67.
PMID: 26061110
Many natural products that consist of quinoline core are found to be bioactive and the versatility of quinoline and its derivatives have attracted great attention in the field of drug...