John Whitesides
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Explore the profile of John Whitesides including associated specialties, affiliations and a list of published articles.
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27
Citations
1064
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Recent Articles
11.
Brodie M, Whitesides J, Schiemann J, DSouza J, Johnson M
Epilepsy Res
. 2016 Sep;
127:114-118.
PMID: 27589414
Introduction: This analysis was conducted to assess the tolerability, safety, and efficacy of brivaracetam (BRV) for adjunctive treatment of focal (partial-onset) seizures in patients aged ≥65 years. Methods: Safety/tolerability and...
12.
Ben-Menachem E, Mameniskiene R, Quarato P, Klein P, Gamage J, Schiemann J, et al.
Neurology
. 2016 Jun;
87(3):314-23.
PMID: 27335114
Objective: To assess the efficacy, safety, and tolerability of adjunctive brivaracetam (BRV), a selective, high-affinity ligand for SV2A, for treatment of partial-onset (focal) seizures (POS) in adults. Methods: Data were...
13.
Toledo M, Whitesides J, Schiemann J, Johnson M, Eckhardt K, McDonough B, et al.
Epilepsia
. 2016 Jun;
57(7):1139-51.
PMID: 27265725
Objectives: To report pooled safety/tolerability and seizure outcome data from adults with uncontrolled partial-onset (focal) seizures (POS) receiving adjunctive brivaracetam (BRV) during phase IIb/III and long-term follow-up (LTFU) studies. Methods:...
14.
Bauer A, Cassel W, Benes H, Kesper K, Rye D, Sica D, et al.
Neurology
. 2016 May;
86(19):1785-93.
PMID: 27164714
Objective: This double-blind, placebo-controlled, interventional trial was conducted to investigate the effects of rotigotine patch on periodic limb movement (PLM)-associated nocturnal systolic blood pressure (SBP) elevations. Methods: Patients with moderate...
15.
Klein P, Schiemann J, Sperling M, Whitesides J, Liang W, Stalvey T, et al.
Epilepsia
. 2015 Oct;
56(12):1890-8.
PMID: 26471380
Objective: Brivaracetam (BRV), a selective and high-affinity synaptic vesicle protein 2A ligand, is in development as adjunctive treatment for partial-onset (focal) seizures (POS). This phase 3 study (N01358; NCT01261325) aimed...
16.
Nicholas A, Borgohain R, Chana P, Surmann E, Thompson E, Bauer L, et al.
J Parkinsons Dis
. 2014 Mar;
4(3):361-73.
PMID: 24643203
Background: Previous phase III studies in patients with advanced Parkinson's disease (PD) not adequately controlled on levodopa demonstrated significant reduction of 'off' time with rotigotine transdermal system up to 16...
17.
Hwang K, Trama A, Kozink D, Chen X, Wiehe K, Cooper A, et al.
PLoS One
. 2014 Mar;
9(3):e90725.
PMID: 24614505
B-cell chronic lymphocytic leukemia (B-CLL) patients expressing unmutated immunoglobulin heavy variable regions (IGHVs) use the IGHV1-69 B cell receptor (BCR) in 25% of cases. Since HIV-1 envelope gp41 antibodies also...
18.
Morris L, Chen X, Alam M, Tomaras G, Zhang R, Marshall D, et al.
PLoS One
. 2011 Oct;
6(9):e23532.
PMID: 21980336
Broadly neutralizing antibodies are not commonly produced in HIV-1 infected individuals nor by experimental HIV-1 vaccines. When these antibodies do occur, it is important to be able to isolate and...
19.
Kim H, Jeon B, Lee W, Lee M, Kim J, Kim J, et al.
BMC Neurol
. 2011 Aug;
11:100.
PMID: 21831297
Background: A recent trial involving predominantly Caucasian subjects with Parkinson Disease (PD) showed switching overnight from an oral dopaminergic agonist to the rotigotine patch was well tolerated without loss of...
20.
Ghys L, Surmann E, Whitesides J, Boroojerdi B
Expert Opin Pharmacother
. 2011 Jul;
12(13):1985-98.
PMID: 21790503
Objective: The aim of this research is to characterize further the potential motor and non-motor benefits of rotigotine reported in the double-blind, placebo-controlled RECOVER trial primary publication, by performing a...