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Michael R Sperling

Explore the profile of Michael R Sperling including associated specialties, affiliations and a list of published articles. Areas
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Articles 324
Citations 6836
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Recent Articles
1.
Halpern D, Lega B, Gross R, Wu C, Sperling M, Aronson J, et al.
Nat Neurosci . 2025 Mar; PMID: 40069364
Can the brain improve the retrievability of an experience after it has occurred? Systems consolidation theory proposes that item-specific cortical reactivation during post-encoding rest periods facilitates the formation of stable...
2.
Citro S, Javidi S, Ankeeta Ankeeta , He X, Zhang Q, Kry Y, et al.
Epilepsia . 2025 Mar; PMID: 40055934
Objective: Subjects with left temporal lobe epilepsy may either show altered hemispheric language lateralization or retain typical, left lateralization. Examining the integrity of white matter pathways involved in the adaptation...
3.
Dave H, McCreary M, Guerra A, Sperling M
Epilepsia . 2025 Feb; PMID: 40019472
Objective: To shorten inpatient epilepsy monitoring unit (EMU) stays during epilepsy surgery evaluation, physicians utilize techniques to induce seizures including antiseizure medication (ASM) reduction, sleep deprivation, and chemical stimulation. We...
4.
Loushy I, Goldstein L, Devlin K, Volski A, Fletman E, Alcala-Zermeno J, et al.
Epilepsia . 2025 Feb; PMID: 39932255
Objective: This study assesses the efficacy, safety, and tolerability of cenobamate using long-term real-world data, incorporating both seizure reduction and seizure-freedom periods, and examines baseline clinical variables to determine predictors...
5.
Myers P, Gunnarsdottir K, Li A, Razskazovskiy V, Craley J, Chandler A, et al.
Ann Neurol . 2025 Jan; PMID: 39817338
Objective: Whereas a scalp electroencephalogram (EEG) is important for diagnosing epilepsy, a single routine EEG is limited in its diagnostic value. Only a small percentage of routine EEGs show interictal...
6.
Alcala-Zermeno J, Romozzi M, Sperling M
Epilepsia . 2025 Jan; PMID: 39754525
Objective: Epilepsy surgery outcomes tend to be judged by the percentage in seizure reduction without considering the effect on specific seizure types, particularly tonic-clonic seizures, which produce the greatest morbidity...
7.
Dimakopoulos V, Gotman J, Klimes P, von Ellenrieder N, Tan S, Smith G, et al.
Brain . 2024 Nov; PMID: 39530262
In drug-resistant focal epilepsy, planning surgical resection may involve presurgical intracranial EEG recordings (iEEG) to detect seizures and other iEEG patterns to improve postsurgical seizure outcome. We hypothesized that resection...
8.
Weiss S, Sperling M, Engel J, Liu A, Fried I, Wu C, et al.
Brain Commun . 2024 Oct; 6(5):fcae367. PMID: 39464217
In medication-resistant epilepsy, the goal of epilepsy surgery is to make a patient seizure free with a resection/ablation that is as small as possible to minimize morbidity. The standard of...
9.
Zhang Q, Hudgins S, Struck A, Ankeeta Ankeeta , Javidi S, Sperling M, et al.
Neurology . 2024 Sep; 103(7):e209800. PMID: 39250744
Background And Objectives: Despite their temporal lobe pathology, a significant subgroup of patients with temporal lobe epilepsy (TLE) is able to maintain normative cognitive functioning. In this study, we identify...
10.
Gill S, Devlin K, Yuan H, Mintzer S, Skidmore C, Wu C, et al.
Neurol Clin Pract . 2024 Aug; 14(6):e200358. PMID: 39185099
Background And Objectives: To compare long-term seizure control in patients with long-term VNS (vagal nerve stimulator) stimulation (VNS-on) with those who discontinued VNS after >3 years (VNS-off). Methods: Patients with...