John W Phillips
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Explore the profile of John W Phillips including associated specialties, affiliations and a list of published articles.
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53
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6370
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Recent Articles
11.
Ding S, Yao Z, Hirokawa K, Nguyen T, Graybuck L, Fong O, et al.
Cell Rep
. 2020 May;
31(7):107648.
PMID: 32433957
Subicular regions play important roles in spatial processing and many cognitive functions, and these are mainly attributed to the subiculum (Sub) rather than the prosubiculum (PS). Using single-cell RNA sequencing,...
12.
Wang Q, Ding S, Li Y, Royall J, Feng D, Lesnar P, et al.
Cell
. 2020 May;
181(4):936-953.e20.
PMID: 32386544
Recent large-scale collaborations are generating major surveys of cell types and connections in the mouse brain, collecting large amounts of data across modalities, spatial scales, and brain areas. Successful integration...
13.
Hodge R, Miller J, Novotny M, Kalmbach B, Ting J, Bakken T, et al.
Nat Commun
. 2020 Mar;
11(1):1172.
PMID: 32127543
von Economo neurons (VENs) are bipolar, spindle-shaped neurons restricted to layer 5 of human frontoinsula and anterior cingulate cortex that appear to be selectively vulnerable to neuropsychiatric and neurodegenerative diseases,...
14.
Phillips J, Pan Y, Tsai B, Xie Z, Demirdjian L, Xiao W, et al.
Proc Natl Acad Sci U S A
. 2020 Feb;
117(10):5269-5279.
PMID: 32086391
We sought to define the landscape of alternative pre-mRNA splicing in prostate cancers and the relationship of exon choice to known cancer driver alterations. To do so, we compiled a...
15.
de Vries S, Lecoq J, Buice M, Groblewski P, Ocker G, Oliver M, et al.
Nat Neurosci
. 2019 Dec;
23(1):138-151.
PMID: 31844315
To understand how the brain processes sensory information to guide behavior, we must know how stimulus representations are transformed throughout the visual cortex. Here we report an open, large-scale physiological...
16.
Harris J, Mihalas S, Hirokawa K, Whitesell J, Choi H, Bernard A, et al.
Nature
. 2019 Nov;
575(7781):195-202.
PMID: 31666704
The mammalian cortex is a laminar structure containing many areas and cell types that are densely interconnected in complex ways, and for which generalizable principles of organization remain mostly unknown....
17.
Hodge R, Bakken T, Miller J, Smith K, Barkan E, Graybuck L, et al.
Nature
. 2019 Aug;
573(7772):61-68.
PMID: 31435019
Elucidating the cellular architecture of the human cerebral cortex is central to understanding our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA-sequencing analysis to perform a comprehensive...
18.
Gouwens N, Sorensen S, Berg J, Lee C, Jarsky T, Ting J, et al.
Nat Neurosci
. 2019 Jun;
22(7):1182-1195.
PMID: 31209381
Understanding the diversity of cell types in the brain has been an enduring challenge and requires detailed characterization of individual neurons in multiple dimensions. To systematically profile morpho-electric properties of...
19.
Bakken T, Hodge R, Miller J, Yao Z, Nguyen T, Aevermann B, et al.
PLoS One
. 2018 Dec;
13(12):e0209648.
PMID: 30586455
Transcriptomic profiling of complex tissues by single-nucleus RNA-sequencing (snRNA-seq) affords some advantages over single-cell RNA-sequencing (scRNA-seq). snRNA-seq provides less biased cellular coverage, does not appear to suffer cell isolation-based transcriptional...
20.
Puchalski R, Shah N, Miller J, Dalley R, Nomura S, Yoon J, et al.
Science
. 2018 May;
360(6389):660-663.
PMID: 29748285
Glioblastoma is an aggressive brain tumor that carries a poor prognosis. The tumor's molecular and cellular landscapes are complex, and their relationships to histologic features routinely used for diagnosis are...