John W Phillips
Overview
Explore the profile of John W Phillips including associated specialties, affiliations and a list of published articles.
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53
Citations
6370
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Recent Articles
1.
Chen X, Yang H, Zhang B, Phillips J, Cheng D, Rigo F, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(28):e2220190120.
PMID: 37399401
The MYC proto-oncogene contributes to the pathogenesis of more than half of human cancers. Malignant transformation by MYC transcriptionally up-regulates the core pre-mRNA splicing machinery and causes misregulation of alternative...
2.
Pan Y, Phillips J, Zhang B, Noguchi M, Kutschera E, McLaughlin J, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(21):e2221116120.
PMID: 37192158
Alternative splicing (AS) is prevalent in cancer, generating an extensive but largely unexplored repertoire of novel immunotherapy targets. We describe soform peptides from NA splicing for mmunotherapy target creening (IRIS),...
3.
Koch C, Svoboda K, Bernard A, Basso M, Churchland A, Fairhall A, et al.
Neuron
. 2022 Oct;
110(22):3661-3666.
PMID: 36240770
We propose centralized brain observatories for large-scale recordings of neural activity in mice and non-human primates coupled with cloud-based data analysis and sharing. Such observatories will advance reproducible systems neuroscience...
4.
Mao Z, Nesterenko P, McLaughlin J, Deng W, Burton Sojo G, Cheng D, et al.
Proc Natl Acad Sci U S A
. 2022 Jul;
119(31):e2203410119.
PMID: 35878026
Tissue-specific antigens can serve as targets for adoptive T cell transfer-based cancer immunotherapy. Recognition of tumor by T cells is mediated by interaction between peptide-major histocompatibility complexes (pMHCs) and T...
5.
Berg J, Sorensen S, Ting J, Miller J, Chartrand T, Buchin A, et al.
Nature
. 2022 Jan;
601(7893):E12.
PMID: 34992294
No abstract available.
6.
Nesterenko P, McLaughlin J, Tsai B, Burton Sojo G, Cheng D, Zhao D, et al.
Cell Rep
. 2021 Dec;
37(13):110167.
PMID: 34919800
Cross-reactivity and direct killing of target cells remain underexplored for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-specific CD8 T cells. Isolation of T cell receptors (TCRs) and overexpression in allogeneic cells...
7.
Berg J, Sorensen S, Ting J, Miller J, Chartrand T, Buchin A, et al.
Nature
. 2021 Oct;
598(7879):151-158.
PMID: 34616067
The neocortex is disproportionately expanded in human compared with mouse, both in its total volume relative to subcortical structures and in the proportion occupied by supragranular layers composed of neurons...
8.
Ding S, Royall J, Lesnar P, Facer B, Smith K, Wei Y, et al.
J Comp Neurol
. 2021 Sep;
530(1):6-503.
PMID: 34525221
Increasing interest in studies of prenatal human brain development, particularly using new single-cell genomics and anatomical technologies to create cell atlases, creates a strong need for accurate and detailed anatomical...
9.
Siegle J, Jia X, Durand S, Gale S, Bennett C, Graddis N, et al.
Nature
. 2021 Jan;
592(7852):86-92.
PMID: 33473216
The anatomy of the mammalian visual system, from the retina to the neocortex, is organized hierarchically. However, direct observation of cellular-level functional interactions across this hierarchy is lacking due to...
10.
Nesterenko P, McLaughlin J, Cheng D, Bangayan N, Burton Sojo G, Seet C, et al.
Proc Natl Acad Sci U S A
. 2021 Jan;
118(3).
PMID: 33431692
T cell receptors (TCRs) are generated by somatic recombination of V/D/J segments to produce up to 10 unique sequences. Highly sensitive and specific techniques are required to isolate and identify...