John W Lumley
Overview
Explore the profile of John W Lumley including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
698
Followers
0
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Related Specialties
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Recent Articles
1.
Mercieca-Bebber R, Eggins R, Brown K, Gebski V, Brewer K, Lai L, et al.
Ann Surg
. 2022 Feb;
277(3):449-455.
PMID: 35166265
Objective: The aim of this study was to compare patient-reported urinary, bowel, and sexual functioning of ALaCaRT Trial participants randomized to open or laparoscopic surgery for rectal cancer. Summary Background...
2.
Keane C, OGrady G, Bissett I, Hayes J, Hulme-Moir M, Eglinton T, et al.
Dis Colon Rectum
. 2021 Nov;
65(7):e698-e706.
PMID: 34775413
Background: Low anterior resection syndrome has a significant impact on the quality of life in rectal cancer survivors. Previous studies comparing laparoscopic to open rectal resection have neglected bowel function...
3.
He Y, Davies C, Harrington B, Hellmers L, Sheng Y, Broomfield A, et al.
Oncogene
. 2019 Sep;
39(1):219-233.
PMID: 31471585
Elevated CUB-domain containing protein 1 (CDCP1) is predictive of colorectal cancer (CRC) recurrence and poor patient survival. While CDCP1 expression identifies stem cell populations that mediate lung metastasis, mechanisms underlying...
4.
Stevenson A, Solomon M, Brown C, Lumley J, Hewett P, Clouston A, et al.
Ann Surg
. 2018 Sep;
269(4):596-602.
PMID: 30247332
Objective: The aim of the study was to determine the efficacy of laparoscopic rectal resection (Lap) versus open laparotomy and rectal resection (Open) for rectal cancer on locoregional recurrence (LRR)...
5.
Chen Y, Harrington B, Lau K, Burke L, He Y, Iconomou M, et al.
J Pharm Biomed Anal
. 2017 Mar;
139:65-72.
PMID: 28279929
CUB domain containing protein 1 (CDCP1) is a transmembrane protein involved in progression of several cancers. When located on the plasma membrane, full-length 135kDa CDCP1 can undergo proteolysis mediated by...
6.
van Iersel J, Paulides T, Verheijen P, Lumley J, Broeders I, Consten E
World J Gastroenterol
. 2016 Jun;
22(21):4977-87.
PMID: 27275090
External and internal rectal prolapse with their affiliated rectocele and enterocele, are associated with debilitating symptoms such as obstructed defecation, pelvic pain and faecal incontinence. Since perineal procedures are associated...
7.
Stevenson A, Solomon M, Lumley J, Hewett P, Clouston A, Gebski V, et al.
JAMA
. 2015 Oct;
314(13):1356-63.
PMID: 26441180
Importance: Laparoscopic procedures are generally thought to have better outcomes than open procedures. Because of anatomical constraints, laparoscopic rectal resection may not be better because of limitations in performing an...
8.
Thompson B, Coory M, Gordon L, Lumley J
Surg Endosc
. 2013 Dec;
28(5):1515-21.
PMID: 24337191
Background: Previous cost analyses of laparoscopic resection for colorectal cancer (CRC) reported slightly higher or similar costs to those of open resection. These analyses were based on randomised controlled trials...
9.
Dong Y, He Y, De Boer L, Stack M, Lumley J, Clements J, et al.
J Biol Chem
. 2012 Feb;
287(13):9792-9803.
PMID: 22315226
Epidermal growth factor (EGF) activation of the EGF receptor (EGFR) is an important mediator of cell migration, and aberrant signaling via this system promotes a number of malignancies including ovarian...
10.
Wortmann A, He Y, Christensen M, Linn M, Lumley J, Pollock P, et al.
J Biol Chem
. 2011 Oct;
286(49):42303-42315.
PMID: 21994943
Reciprocal interactions between Src family kinases (SFKs) and focal adhesion kinase (FAK) are critical during changes in cell attachment. Recently it has been recognized that another SFK substrate, CUB-domain-containing protein...