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John W Craft Jr

Explore the profile of John W Craft Jr including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 182
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Recent Articles
1.
Reyes-Alcaraz A, Qasim H, Merlinsky E, Fox G, Islam T, Medina B, et al.
Biomedicines . 2023 Mar; 11(3). PMID: 36979895
The COVID-19 pandemic has underscored the urgent need to develop highly potent and safe medications that are complementary to the role of vaccines. Specifically, it has exhibited the need for...
2.
Hickman A, Koetsier J, Kurtanich T, Nielsen M, Winn G, Wang Y, et al.
J Clin Invest . 2022 May; 132(13). PMID: 35552271
The inability of CD8+ effector T cells (Teffs) to reach tumor cells is an important aspect of tumor resistance to cancer immunotherapy. The recruitment of these cells to the tumor...
3.
St Hill L, Craft Jr J, Chinwangso P, Tran H, Marquez M, Lee T
ACS Appl Bio Mater . 2022 Jan; 4(2):1563-1572. PMID: 35006665
Biofouling negatively impacts modern society on a daily basis, especially with regard to the important industries of medicine, oil, and shipping. This manuscript describes the preparation and study of model...
4.
Bakthavatsalam D, Craft Jr J, Kazansky A, Nguyen N, Bae G, Caivano A, et al.
Front Immunol . 2021 Jan; 11:575085. PMID: 33488575
Leukocyte inflammatory responses require integrin cell-adhesion molecule signaling through spleen tyrosine kinase (Syk), a non-receptor kinase that binds directly to integrin β-chain cytoplasmic domains. Here, we developed a high-throughput screen...
5.
Abbasgholizadeh R, Zhang H, Craft Jr J, Bryan Jr R, Bark S, Briggs J, et al.
Exp Biol Med (Maywood) . 2019 May; 244(11):940-951. PMID: 31132884
No abstract available.
6.
Kurakula K, Koenis D, Herzik Jr M, Liu Y, Craft Jr J, van Loenen P, et al.
Haematologica . 2018 Mar; 103(6):1073-1082. PMID: 29545340
Tissue Factor is a cell-surface glycoprotein expressed in various cells of the vasculature and is the principal regulator of the blood coagulation cascade and hemostasis. Notably, aberrant expression of Tissue...
7.
Woodside D, Tanifum E, Ghaghada K, Biediger R, Caivano A, Starosolski Z, et al.
Sci Rep . 2018 Mar; 8(1):3733. PMID: 29487319
Inflammation drives the degradation of atherosclerotic plaque, yet there are no non-invasive techniques available for imaging overall inflammation in atherosclerotic plaques, especially in the coronary arteries. To address this, we...
8.
Cherubin P, Garcia M, Curtis D, Britt C, Craft Jr J, Burress H, et al.
PLoS One . 2016 Nov; 11(11):e0166477. PMID: 27829022
Cholera toxin (CT) is an AB-type protein toxin that contains a catalytic A1 subunit, an A2 linker, and a cell-binding B homopentamer. The CT holotoxin is released into the extracellular...
9.
Craft Jr J, Shen T, Brier L, Briggs J
J Phys Chem B . 2014 Oct; 119(3):1048-61. PMID: 25322200
The biophysical chemistry of macromolecular complexes confer their functional characteristics. We investigate the mechanisms that make the AB5 holotoxin of Vibrio cholerae (CT) a significantly more pathogenic molecule than the...
10.
Craft Jr J, Zhang H, Charendoff M, Mindrebo J, Schwartz R, Briggs J
J Mol Graph Model . 2013 Oct; 46:74-82. PMID: 24149321
Rho-associated kinase, or ROCK, is an important mediator of ventricular remodeling in cardiac hypertrophy. It has a kinase catalytic domain, a coiled-coil domain and a Pleckstrin-Homology domain (PH domain) with...