John T Vaage
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Explore the profile of John T Vaage including associated specialties, affiliations and a list of published articles.
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37
Citations
365
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Recent Articles
21.
Kveberg L, Dai K, Inngjerdingen M, Brooks C, Fossum S, Vaage J
Immunogenetics
. 2011 Mar;
63(7):429-36.
PMID: 21409442
Two clusters of rat Nkrp1 genes can be distinguished based on phylogenetic relationships and functional characteristics. The proximal (centromeric) cluster encodes the well-studied NKR-P1A and NKR-P1B receptors and the distal...
22.
Zinocker S, Wang M, Gaustad P, Kvalheim G, Rolstad B, Vaage J
PLoS One
. 2011 Jan;
6(1):e16005.
PMID: 21264307
Background: Mesenchymal stromal cells (MSC) have important immunomodulatory effects that can be exploited in the clinical setting, e.g. in patients suffering from graft-versus-host disease after allogeneic stem cell transplantation. In...
23.
Shegarfi H, Dai K, Daws M, Ryan J, Vaage J, Rolstad B, et al.
J Leukoc Biol
. 2011 Jan;
89(4):617-23.
PMID: 21248147
Ly49 receptors in rodents, like KIRs in humans, regulate NK cell activity. Although inhibitory Ly49 receptors clearly recognize MHC-I molecules, ligands for the activating Ly49 receptors are less well defined....
24.
Naper C, Kveberg L, Engh E, Nestvold J, Rolstad B, Vaage J
Int Immunol
. 2010 Dec;
22(12):973-80.
PMID: 21118904
We have studied the effect of radioresistant host cells in inducing tolerance and adaptation of the MHC recognition repertoire of donor-derived NK cells in stem cell allotransplanted (allo-SCT) rats. Sub-lethally...
25.
Shegarfi H, Dai K, Inngjerdingen M, Ryan J, Vaage J, Rolstad B, et al.
Eur J Immunol
. 2010 Nov;
40(12):3535-43.
PMID: 21108473
We have investigated whether rat Ly49 receptors can monitor Listeria-infected intestinal epithelial cells through altered expression of MHC class I molecules. The rat colon carcinoma epithelial cell line CC531 infected...
26.
Kveberg L, Jimenez-Royo P, Naper C, Rolstad B, Butcher G, Vaage J, et al.
J Leukoc Biol
. 2010 Apr;
88(1):87-93.
PMID: 20395458
Two major subsets of rat NK cells can be distinguished based on their expression of the Ly49s3 or the NKR-P1B lectin-like receptor. Ly49s3(+) NK cells, but not NKR-P1B(+) NK cells,...
27.
Kveberg L, Dai K, Westgaard I, Daws M, Fossum S, Naper C, et al.
Eur J Immunol
. 2009 Jan;
39(2):541-51.
PMID: 19130483
A major subset of non-alloreactive NK cells in PVG strain rats is generally low in Ly49 receptors, but expresses the rat NKR-P1B(PVG) receptor (previously termed NKR-P1C). The NKR-P1B(+) NK subset...
28.
Nestvold J, Omdal B, Dai K, Martens A, Benestad H, Vaage J, et al.
Transplantation
. 2008 Jan;
85(1):102-11.
PMID: 18192919
Background: We have employed a rat model for human acute myeloid leukemia, a promyelocytic leukemia in the BN rat strain (BNML), to develop new protocols for immunotherapy in combination with...
29.
Kveberg L, Dai K, Dissen E, Ryan J, Rolstad B, Vaage J, et al.
Immunogenetics
. 2006 Oct;
58(11):905-16.
PMID: 17028855
Natural killer (NK) cells from certain rat strains promptly kill MHC allogeneic lymphocytes in vivo, a rejection phenomenon termed allogeneic lymphocyte cytotoxicity (ALC). ALC can be reproduced in vitro, and...
30.