John T Vaage
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Explore the profile of John T Vaage including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Kjeldsen-Kragh J, Titze T, Lie B, Vaage J, Kjaer M
Blood Adv
. 2019 Mar;
3(7):945-951.
PMID: 30923048
HLA-DRB3*01:01 is a predisposing factor for human platelet antigen 1a (HPA-1a) immunization, which is responsible for most cases of fetal and neonatal alloimmune thrombocytopenia. The aim of this study was...
12.
Dai K, Ryan J, Naper C, Vaage J
J Immunol
. 2018 Mar;
200(8):2847-2859.
PMID: 29531166
Early studies indicate that rats may have a repertoire of MHC class Ib-reactive Ly49 stimulatory receptors capable of mounting memory-like NK cell alloresponses. In this article, we provide molecular and...
13.
Sudworth A, Vaage J, Inngjerdingen M, Kveberg L
J Leukoc Biol
. 2017 Jul;
102(6):1289-1298.
PMID: 28747319
Rat NK cells are divided into major subsets expressing either Ly49 receptors or the inhibitory NKR-P1B receptor in conjunction with NKG2A/C/E receptors. A minor subset of NKp46 cells lacking expression...
14.
Sudworth A, Dai K, Vaage J, Kveberg L
Front Immunol
. 2016 Dec;
7:572.
PMID: 28003815
Measuring degranulation through CD107a expression has become an advantageous tool for testing the functional capacity of cytotoxic cells. Such functional studies have been hampered in the rat by the lack...
15.
Kveberg L, Sudworth A, Todros-Dawda I, Inngjerdingen M, Vaage J
Eur J Immunol
. 2014 Nov;
45(2):501-12.
PMID: 25382546
Natural killer cell receptor protein 1 (NKR-P1) molecules are C-type lectin-like receptors modulating cellular responses toward target cells expressing C-type lectin-like related (Clr) molecules. Although the function of the prototypic...
16.
Todros-Dawda I, Kveberg L, Vaage J, Inngjerdingen M
PLoS One
. 2014 May;
9(5):e97844.
PMID: 24832104
NK cells express several tetraspanin proteins, which differentially modulate NK cell activities. The tetraspanin CD53 is expressed by all resting NK cells and was previously shown to decrease NK cell...
17.
Smelt M, Faas M, de Haan B, de Haan A, Vaage J, de Vos P
Cell Transplant
. 2013 Jul;
23(11):1381-94.
PMID: 23866824
There are still many factors to discover to explain the low success rates of islet allografts. In this study, we demonstrate that specific subpopulations of alloreactive NK cells may be...
18.
Daws M, Dai K, Zinocker S, Naper C, Kveberg L, Hedrich H, et al.
J Immunol
. 2012 Oct;
189(11):5178-84.
PMID: 23100519
Natural killer cells are able to recognize and kill target cells according to differences in MHC class I expression. In rodents, the Ly49 receptors are primarily responsible for this MHC...
19.
Zinocker S, Vaage J
Front Immunol
. 2012 May;
3:62.
PMID: 22566943
Mesenchymal stromal cells (MSC) have important immunomodulatory properties, they inhibit T lymphocyte allo-activation and have been used to treat graft-versus-host disease. How MSC exert their immunosuppressive functions is not completely...
20.
Inngjerdingen M, Kveberg L, Vaage J
J Immunol
. 2012 Feb;
188(6):2499-508.
PMID: 22308308
The inhibitory NKR-P1B receptor identifies a subset of rat splenic NK cells that is low in Ly49 receptors but enriched for CD94/NKG2 receptors. We report in this study a novel...