John Samuelson
Overview
Explore the profile of John Samuelson including associated specialties, affiliations and a list of published articles.
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Articles
58
Citations
1958
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Recent Articles
1.
Kanakapura Sundararaj B, Goyal M, Samuelson J
mSphere
. 2025 Mar;
:e0094824.
PMID: 40035521
, which are free-living amoebae, cause corneal inflammation (keratitis) and blindness, if not quickly diagnosed and effectively treated. The walls of cysts contain cellulose and have two layers connected by...
2.
Tiwari M, Gas-Pascual E, Goyal M, Popov M, Matsumoto K, Grafe M, et al.
bioRxiv
. 2024 Oct;
PMID: 39464065
Cellular adaptations to change often involve post-translational modifications of nuclear and cytoplasmic proteins. An example found in protists and plants is the modification of serine and threonine residues of dozens...
3.
Kanakapura Sundararaj B, Goyal M, Samuelson J
bioRxiv
. 2024 Oct;
PMID: 39463995
Importance: Free-living amoeba in the soil or water cause keratitis, which is diagnosed by identification of cysts by microscopy of the eye or of corneal scrapings, using calcofluor-white that unfortunately...
4.
Kanakapura Sundararaj B, Goyal M, Samuelson J
mSphere
. 2024 Aug;
9(9):e0046624.
PMID: 39136454
The cyst wall of the eye pathogen contains cellulose and has ectocyst and endocyst layers connected by conical ostioles. Cyst walls contain families of lectins that localize to the ectocyst...
5.
van der Wel H, Garcia A, Gas-Pascual E, Willis M, Kim H, Bandini G, et al.
Glycobiology
. 2022 Oct;
33(3):225-244.
PMID: 36250576
O-GlcNAcylation is a prominent modification of nuclear and cytoplasmic proteins in animals and plants and is mediated by a single O-GlcNAc transferase (OGT). Spindly (Spy), a paralog of OGT first...
6.
Bandini G, Agop-Nersesian C, van der Wel H, Mandalasi M, Kim H, West C, et al.
J Biol Chem
. 2020 Nov;
296:100039.
PMID: 33158988
Once considered unusual, nucleocytoplasmic glycosylation is now recognized as a conserved feature of eukaryotes. While in animals, O-GlcNAc transferase (OGT) modifies thousands of intracellular proteins, the human pathogen Toxoplasma gondii...
7.
Magistrado-Coxen P, Aqeel Y, Lopez A, Haserick J, Urbanowicz B, Costello C, et al.
PLoS Negl Trop Dis
. 2019 May;
13(5):e0007352.
PMID: 31095564
Background: Acanthamoeba castellanii, which causes keratitis and blindness in under-resourced countries, is an emerging pathogen worldwide, because of its association with contact lens use. The wall makes cysts resistant to...
8.
Bandini G, Albuquerque-Wendt A, Hegermann J, Samuelson J, Routier F
Parasitology
. 2019 Feb;
146(14):1755-1766.
PMID: 30773146
Apicomplexan parasites are amongst the most prevalent and morbidity-causing pathogens worldwide. They are responsible for severe diseases in humans and livestock and are thus of great public health and economic...
9.
Bandini G, Leon D, Hoppe C, Zhang Y, Agop-Nersesian C, Shears M, et al.
J Biol Chem
. 2018 Dec;
294(6):1967-1983.
PMID: 30538131
is an intracellular parasite that causes disseminated infections that can produce neurological damage in fetuses and immunocompromised individuals. Microneme protein 2 (MIC2), a member of the thrombospondin-related anonymous protein (TRAP)...
10.
Gas-Pascual E, Ichikawa H, Sheikh M, Serji M, Deng B, Mandalasi M, et al.
J Biol Chem
. 2018 Nov;
294(4):1104-1125.
PMID: 30463938
Infection with the protozoan parasite is a major health risk owing to birth defects, its chronic nature, ability to reactivate to cause blindness and encephalitis, and high prevalence in human...