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John R Lamb

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Articles 25
Citations 3487
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Recent Articles
1.
Bankier S, Gudmundsdottir V, Jonmundsson T, Bjarnadottir H, Loureiro J, Wang L, et al.
medRxiv . 2025 Feb; PMID: 39974043
Variations in blood protein levels have been associated with a broad spectrum of complex diseases, including atherosclerotic cardiovascular disease (ACVD). These associations highlight the intricate interplay between local (e.g., cardiovascular)...
2.
Emilsson V, Jonsson B, Austin T, Gudmundsdottir V, Axelsson G, Frick E, et al.
Eur J Heart Fail . 2023 Nov; 26(1):87-102. PMID: 37936531
Aim: To examine the ability of serum proteins in predicting future heart failure (HF) events, including HF with reduced or preserved ejection fraction (HFrEF or HFpEF), in relation to event...
3.
Emilsson V, Gudmundsson E, Jonmundsson T, Jonsson B, Twarog M, Gudmundsdottir V, et al.
Nat Commun . 2022 Jun; 13(1):3401. PMID: 35697682
Age-related macular degeneration (AMD) is one of the most common causes of visual impairment in the elderly, with a complex and still poorly understood etiology. Whole-genome association studies have discovered...
4.
Emilsson V, Gudmundsdottir V, Gudjonsson A, Jonmundsson T, Jonsson B, Karim M, et al.
Nat Commun . 2022 Jan; 13(1):481. PMID: 35079000
Circulating proteins can be used to diagnose and predict disease-related outcomes. A deep serum proteome survey recently revealed close associations between serum protein networks and common disease. In the current...
5.
Gudjonsson A, Gudmundsdottir V, Axelsson G, Gudmundsson E, Jonsson B, Launer L, et al.
Nat Commun . 2022 Jan; 13(1):480. PMID: 35078996
With the growing number of genetic association studies, the genotype-phenotype atlas has become increasingly more complex, yet the functional consequences of most disease associated alleles is not understood. The measurement...
6.
Emilsson V, Gudmundsson E, Aspelund T, Jonsson B, Gudjonsson A, Launer L, et al.
Obes Sci Pract . 2021 Apr; 7(2):239-243. PMID: 33841894
Objective: As severity of outcome in COVID-19 is disproportionately higher among individuals with obesity, smokers, patients with hypertension, kidney disease, chronic pulmonary disease, coronary heart disease (CHD), and/or type 2...
7.
Lamb J, Jennings L, Gudmundsdottir V, Gudnason V, Emilsson V
Trends Mol Med . 2020 Sep; 27(1):20-30. PMID: 32988739
Recent advances in protein profiling technology has facilitated simultaneous measurement of thousands of proteins in large population studies, exposing the depth and complexity of the plasma and serum proteomes. This...
8.
Emilsson V, Gudmundsson E, Aspelund T, Jonsson B, Gudjonsson A, Launer L, et al.
medRxiv . 2020 Jun; PMID: 32511628
Aims: Severity of outcome in COVID-19 is disproportionately higher among the obese, males, smokers, those suffering from hypertension, kidney disease, coronary heart disease (CHD) and/or type 2 diabetes (T2D). We...
9.
Gudmundsdottir V, Zaghlool S, Emilsson V, Aspelund T, Ilkov M, Gudmundsson E, et al.
Diabetes . 2020 May; 69(8):1843-1853. PMID: 32385057
The increasing prevalence of type 2 diabetes poses a major challenge to societies worldwide. Blood-based factors like serum proteins are in contact with every organ in the body to mediate...
10.
Cheng H, Deaton L, Qiu M, Ha S, Pacoma R, Lao J, et al.
Neurobiol Dis . 2019 Nov; 134:104683. PMID: 31765727
Repeated mild traumatic brain injury (rmTBI) can lead to development of chronic traumatic encephalopathy (CTE), which is characterized by progressive neurodegeneration with presence of white matter damage, gliosis and hyper-phosphorylated...