John R Klem
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Explore the profile of John R Klem including associated specialties, affiliations and a list of published articles.
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3
Citations
10
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Recent Articles
1.
Klem J, Schwantes-An T, Abreu M, Suttie M, Gray R, Vo H, et al.
Dis Model Mech
. 2025 Mar;
PMID: 40067253
Fetal Alcohol Spectrum Disorders (FASD) describe ethanol-induced developmental defects including craniofacial malformations. While ethanol-sensitive genetic mutations contribute to facial malformations, the impacted cellular mechanisms remain unknown. Bmp signaling is a...
2.
Klem J, Schwantes-An T, Abreu M, Suttie M, Gray R, Vo H, et al.
bioRxiv
. 2023 Jul;
PMID: 37425959
Summary Statement: In this study, we apply a unique combination of zebrafish-based approaches and human genetic and facial dysmorphology analyses to resolve the cellular mechanisms driven by the ethanol-sensitive Bmp...
3.
Kemmler C, Moran H, Murray B, Scoresby A, Klem J, Eckert R, et al.
Development
. 2023 Mar;
150(8).
PMID: 36975217
Transgenesis is an essential technique for any genetic model. Tol2-based transgenesis paired with Gateway-compatible vector collections has transformed zebrafish transgenesis with an accessible modular system. Here, we establish several next-generation...
4.
Klem J, Gray R, Lovely C
J Vis Exp
. 2022 Dec;
(189).
PMID: 36533820
Fetal alcohol spectrum disorders (FASD) are characterized by a highly variable set of structural defects and cognitive impairments that arise due to prenatal ethanol exposure. Due to the complex pathology...