John R Kelsoe
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Explore the profile of John R Kelsoe including associated specialties, affiliations and a list of published articles.
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147
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6328
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Recent Articles
11.
Mishra H, Wei H, Rohr K, Ko I, Nievergelt C, Maihofer A, et al.
Eur Neuropsychopharmacol
. 2023 May;
74:1-14.
PMID: 37126998
Bipolar disorder (BD) is characterized by mood episodes, disrupted circadian rhythms and gray matter reduction in the brain. Lithium is an effective pharmacotherapy for BD, but not all patients respond...
12.
Niemsiri V, Rosenthal S, Nievergelt C, Maihofer A, Marchetto M, Santos R, et al.
Mol Psychiatry
. 2023 Mar;
29(1):6-19.
PMID: 36991131
Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this...
13.
14.
Mishra H, Mandyam A, Trenet W, Wei H, Nievergelt C, Maihofer A, et al.
Neuropharmacology
. 2023 Jan;
226:109410.
PMID: 36608815
Bipolar disorder (BD) is characterized by manic and depressive mood episodes and loss of brain gray matter. Lithium has antimanic and neuroprotective properties, but only 30% BD patients respond to...
15.
Coombes B, Millischer V, Batzler A, Larrabee B, Hou L, Papiol S, et al.
Complex Psychiatry
. 2022 Nov;
7(3-4):80-89.
PMID: 36408127
Response to lithium varies widely between individuals with bipolar disorder (BD). Polygenic risk scores (PRSs) can uncover pharmacogenomics effects and may help predict drug response. Patients ( = 2,510) with...
16.
Minassian A, Kelsoe J, Miranda A, Young J, Perry W
Psychiatry Res
. 2022 Aug;
316:114776.
PMID: 35964417
Novelty seeking is a tendency to approach new situations, putatively driven by the brain's catecholaminergic system. It is traditionally measured via self-report, but a laboratory-based paradigm, the human Behavioral Pattern...
17.
Greenwood T, Chow L, Gur R, Kelsoe J
J Psychiatr Res
. 2022 Jul;
153:149-158.
PMID: 35816974
Creativity has long been associated with the bipolar spectrum, particularly among unaffected first-degree relatives and those with milder expressions of bipolar traits, suggesting that some aspects of the bipolar spectrum...
18.
Hasin N, Riggs L, Shekhtman T, Ashworth J, Lease R, Oshone R, et al.
Mol Psychiatry
. 2022 May;
27(9):3842-3856.
PMID: 35546635
Bipolar disorder is an often-severe mental health condition characterized by alternation between extreme mood states of mania and depression. Despite strong heritability and the recent identification of 64 common variant...
19.
Kalman J, Yoshida T, Andlauer T, Schulte E, Adorjan K, Alda M, et al.
Eur Arch Psychiatry Clin Neurosci
. 2022 Feb;
272(8):1611-1620.
PMID: 35146571
Personality traits influence risk for suicidal behavior. We examined phenotype- and genotype-level associations between the Big Five personality traits and suicidal ideation and attempt in major depressive, bipolar and schizoaffective...
20.
Kalman J, Olde Loohuis L, Vreeker A, McQuillin A, Stahl E, Ruderfer D, et al.
Br J Psychiatry
. 2022 Jan;
219(6):659-669.
PMID: 35048876
Background: Studying phenotypic and genetic characteristics of age at onset (AAO) and polarity at onset (PAO) in bipolar disorder can provide new insights into disease pathology and facilitate the development...