Francis J McMahon
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Explore the profile of Francis J McMahon including associated specialties, affiliations and a list of published articles.
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186
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9280
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Recent Articles
1.
Smith R, Mihalik A, Akula N, Auluck P, Marenco S, Raznahan A, et al.
bioRxiv
. 2025 Feb;
PMID: 39990369
Many genes are linked to psychiatric disorders, but genome-wide association studies (GWAS) and differential gene expression (DGE) analyses in post-mortem brain tissue often implicate distinct gene sets. This disconnect impedes...
2.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature
. 2025 Jan;
PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
3.
Development and early life stress sensitivity of the rat cortical microstructural similarity network
Smith R, Sawiak S, Dorfschmidt L, Dutcher E, Jones J, Hahn J, et al.
bioRxiv
. 2025 Jan;
PMID: 39803427
The rat offers a uniquely valuable animal model in neuroscience, but we currently lack an individual-level understanding of the in vivo rat brain network. Here, leveraging longitudinal measures of cortical...
4.
Arbona-Lampaya A, Sung H, DAmico A, Knowles E, Besancon E, Freifeld A, et al.
J Affect Disord
. 2024 Dec;
372():394-401.
PMID: 39667704
Background: Bipolar disorder (BD) presents with a wide range of symptoms that vary among relatives, casting doubt on categorical illness models. To address this uncertainty, we investigated the heritability and...
5.
Donohue B, Gao S, Nichols T, Adhikari B, Ma Y, Jahanshad N, et al.
Hum Brain Mapp
. 2024 Nov;
45(17):e70044.
PMID: 39593222
National and international biobanking efforts led to the collection of large and inclusive imaging genetics datasets that enable examination of the contribution of genetic and environmental factors to human brains...
6.
Schulmann A, Feng N, Auluck P, Mukherjee A, Komal R, Leng Y, et al.
bioRxiv
. 2024 Sep;
PMID: 39282422
The mediodorsal thalamus (MD) and adjacent midline nuclei are important for cognition and mental illness, but their cellular composition is not well defined. Using single-nucleus and spatial transcriptomics, we identified...
7.
Feng N, Mandal A, Jambhale A, Narnur P, Chen G, Akula N, et al.
Hum Mol Genet
. 2024 Sep;
33(22):1939-1947.
PMID: 39239979
Common variants in the MicroRNA 137 host gene MIR137HG and its adjacent gene DPYD have been associated with schizophrenia risk and the latest Psychiatric Genomics Consortium (PGC). Genome-Wide Association Study...
8.
Arasappan D, Spears A, Shah S, Mayfield R, Akula N, McMahon F, et al.
bioRxiv
. 2024 Aug;
PMID: 39185191
Mood disorders affect over ten percent of humans, but studies dissecting the brain anatomical and molecular neurobiological mechanisms underlying mood (dys)functions have not consistently identified the patterns of pathological changes...
9.
DAmico A, Sung H, Arbona-Lampaya A, Freifeld A, Hosey K, Garcia J, et al.
Am J Med Genet B Neuropsychiatr Genet
. 2024 Jul;
198(1):e33001.
PMID: 39011872
Cognitive deficits in people with bipolar disorder (BD) may be the result of the illness or its treatment, but they could also reflect genetic risk factors shared between BD and...
10.
Strom N, Verhulst B, Bacanu S, Cheesman R, Purves K, Gedik H, et al.
medRxiv
. 2024 Jul;
PMID: 39006447
The major anxiety disorders (ANX; including generalized anxiety disorder, panic disorder, and phobias) are highly prevalent, often onset early, persist throughout life, and cause substantial global disability. Although distinct in...