John R Bradley
Overview
Explore the profile of John R Bradley including associated specialties, affiliations and a list of published articles.
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80
Citations
6399
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Recent Articles
1.
Humphrey T, Qian W, Chen-Xu M, Dowling F, Gatley K, Adhikari R, et al.
BMC Infect Dis
. 2025 Feb;
25(1):204.
PMID: 39934669
Purpose: Despite vaccination, many patients remain vulnerable to COVID-19 infection and poorer outcomes, because of underlying health conditions resulting in sub-optimal vaccine responses. This study aims to demonstrate whether intranasal...
2.
Shil R, Seed A, Franklyn N, Sargent B, Wood G, Huang Y, et al.
Sci Rep
. 2025 Jan;
15(1):3443.
PMID: 39870668
It is established that patients hospitalised with COVID-19 often have ongoing morbidity affecting activity of daily living (ADL), employment, and mental health. However, little is known about the relative outcomes...
3.
Rahman M, Harrison E, Biggs H, Seikus C, Elliott P, Breen G, et al.
Nat Med
. 2024 May;
30(6):1739-1748.
PMID: 38745010
A leading explanation for translational failure in neurodegenerative disease is that new drugs are evaluated late in the disease course when clinical features have become irreversible. Here, to address this...
4.
Michael B, Dunai C, Needham E, Tharmaratnam K, Williams R, Huang Y, et al.
Nat Commun
. 2024 Apr;
15(1):2918.
PMID: 38575615
No abstract available.
5.
Al-Lamki R, Tolkovsky A, Alawwami M, Lu W, Field S, Wang J, et al.
Am J Pathol
. 2024 Mar;
194(7):1374-1387.
PMID: 38537932
Clear-cell renal cell carcinoma (ccRCC), a tubular epithelial malignancy, secretes tumor necrosis factor (TNF), which signals ccRCC cells in an autocrine manner via two cell surface receptors, TNFR1 and TNFR2,...
6.
Hanson A, Mule M, Ruffieux H, Mescia F, Bergamaschi L, Pelly V, et al.
Nat Immunol
. 2024 Mar;
25(3):471-482.
PMID: 38429458
Persistent symptoms following SARS-CoV-2 infection are increasingly reported, although the drivers of post-acute sequelae (PASC) of COVID-19 are unclear. Here we assessed 214 individuals infected with SARS-CoV-2, with varying disease...
7.
Krishna B, Lim E, Metaxaki M, Jackson S, Mactavous L, Lyons P, et al.
Sci Adv
. 2024 Feb;
10(8):eadi9379.
PMID: 38381822
After acute infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a proportion of patients experience persistent symptoms beyond 12 weeks, termed Long Covid. Understanding the mechanisms that cause this debilitating...
8.
Priddey A, Chen-Xu M, Cooper D, MacMillan S, Meisl G, Xu C, et al.
Front Immunol
. 2024 Jan;
14:1296148.
PMID: 38259440
Background: Patients with autoimmune/inflammatory conditions on anti-CD20 therapies, such as rituximab, have suboptimal humoral responses to vaccination and are vulnerable to poorer clinical outcomes following SARS-CoV-2 infection. We aimed to...
9.
Michael B, Dunai C, Needham E, Tharmaratnam K, Williams R, Huang Y, et al.
Nat Commun
. 2023 Dec;
14(1):8487.
PMID: 38135686
To understand neurological complications of COVID-19 better both acutely and for recovery, we measured markers of brain injury, inflammatory mediators, and autoantibodies in 203 hospitalised participants; 111 with acute sera...
10.
Monssen D, Davies H, Kakar S, Bristow S, Curzons S, Davies M, et al.
Int J Eat Disord
. 2023 Aug;
57(5):1145-1159.
PMID: 37584261
Objective: The United Kingdom Eating Disorders Genetics Initiative (EDGI UK), part of the National Institute for Health and Care Research (NIHR) Mental Health BioResource, aims to deepen our understanding of...