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John R Bradley

Explore the profile of John R Bradley including associated specialties, affiliations and a list of published articles. Areas
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Articles 80
Citations 6399
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Recent Articles
11.
McMahon A, Kaptoge S, Walker M, Mehenny S, Gilchrist P, Sambrook J, et al.
Trials . 2023 Aug; 24(1):512. PMID: 37563721
Background: Vasovagal reactions (VVRs) are the most common acute complications of blood donation. Responsible for substantial morbidity, they also reduce the likelihood of repeated donations and are disruptive and costly...
12.
Potts M, Fletcher-Etherington A, Nightingale K, Mescia F, Bergamaschi L, Calero-Nieto F, et al.
Cell Rep . 2023 Jun; 42(6):112613. PMID: 37302069
Certain serum proteins, including C-reactive protein (CRP) and D-dimer, have prognostic value in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Nonetheless, these factors are non-specific, providing limited mechanistic...
13.
Ruffieux H, Hanson A, Lodge S, Lawler N, Whiley L, Gray N, et al.
Nat Immunol . 2023 Jan; 24(2):349-358. PMID: 36717723
The biology driving individual patient responses to severe acute respiratory syndrome coronavirus 2 infection remains ill understood. Here, we developed a patient-centric framework leveraging detailed longitudinal phenotyping data and covering...
14.
Herrero-Zazo M, Fitzgerald T, Taylor V, Street H, Chaudhry A, Bradley J, et al.
iScience . 2023 Jan; 26(1):105876. PMID: 36691609
Electronic Health Records (EHR) data can provide novel insights into inpatient trajectories. Blood tests and vital signs from de-identified patients' hospital admission episodes (AE) were represented as multivariate time-series (MVTS)...
15.
Tsvetanov K, Spindler L, Stamatakis E, Newcombe V, Lupson V, Chatfield D, et al.
Neuroimage Clin . 2022 Dec; 36:103253. PMID: 36451358
Human coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has multiple neurological consequences, but its long-term effect on brain health is still uncertain. The cerebrovascular consequences...
16.
Needham E, Ren A, Digby R, Norton E, Ebrahimi S, Outtrim J, et al.
Brain . 2022 Sep; 145(11):4097-4107. PMID: 36065116
COVID-19 is associated with neurological complications including stroke, delirium and encephalitis. Furthermore, a post-viral syndrome dominated by neuropsychiatric symptoms is common, and is seemingly unrelated to COVID-19 severity. The true...
17.
Cooper D, Lear S, Watson L, Shaw A, Ferris M, Doffinger R, et al.
J Infect . 2022 Sep; 85(5):557-564. PMID: 36058413
Objectives: To describe the risk factors for SARS-CoV-2 infection in UK healthcare workers (HCWs). Methods: We conducted a prospective sero-epidemiological study of HCWs at a major UK teaching hospital using...
18.
Meng B, Datir R, Choi J, Bradley J, Smith K, Lee J, et al.
Cell Rep . 2022 Aug; 40(7):111220. PMID: 35963244
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike N-terminal domain (NTD) remains poorly characterized despite enrichment of mutations in this region across variants of concern (VOCs). Here, we examine...
19.
Kemp S, Collier D, Datir R, Ferreira I, Gayed S, Jahun A, et al.
Nature . 2022 Jul; 608(7922):E23. PMID: 35864233
No abstract available.
20.
Collier D, De Marco A, Ferreira I, Meng B, Datir R, Walls A, et al.
Nature . 2022 Jul; 608(7922):E24. PMID: 35864232
No abstract available.