John Parsch
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Explore the profile of John Parsch including associated specialties, affiliations and a list of published articles.
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52
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2173
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Recent Articles
1.
Glaser-Schmitt A, Lemoine M, Kaltenpoth M, Parsch J
PLoS Genet
. 2024 Aug;
20(8):e1011257.
PMID: 39178312
The pervasiveness of gene expression variation and its contribution to phenotypic variation and evolution is well known. This gene expression variation is context dependent, with differences in regulatory architecture often...
2.
Grandchamp A, Kuhl L, Lebherz M, Bruggemann K, Parsch J, Bornberg-Bauer E
Genome Res
. 2023 Jul;
33(6):872-890.
PMID: 37442576
Novel genes are essential for evolutionary innovations and differ substantially even between closely related species. Recently, multiple studies across many taxa showed that some novel genes arise de novo, that...
3.
Glaser-Schmitt A, Ramnarine T, Parsch J
Mol Ecol
. 2023 May;
33(10):e17024.
PMID: 37222070
Allele frequencies can shift rapidly within natural populations. Under certain conditions, repeated rapid allele frequency shifts can lead to the long-term maintenance of polymorphism. In recent years, studies of the...
4.
Glaser-Schmitt A, Parsch J
PLoS Genet
. 2023 Apr;
19(4):e1010730.
PMID: 37099612
Gene expression variation is pervasive across all levels of organismal organization, including development. Few studies, however, have examined variation in developmental transcriptional dynamics among populations, or how it contributes to...
5.
Ramnarine T, Grath S, Parsch J
G3 (Bethesda)
. 2021 Nov;
12(1).
PMID: 34747443
Broadly distributed species must cope with diverse and changing environmental conditions, including various forms of stress. Cosmopolitan populations of Drosophila melanogaster are more tolerant to oxidative stress than those from...
6.
Kapun M, Nunez J, Bogaerts-Marquez M, Murga-Moreno J, Paris M, Outten J, et al.
Mol Biol Evol
. 2021 Sep;
38(12):5782-5805.
PMID: 34469576
Drosophila melanogaster is a leading model in population genetics and genomics, and a growing number of whole-genome data sets from natural populations of this species have been published over the...
7.
Wallace M, Coffman K, Gilbert C, Ravindran S, Albery G, Abbott J, et al.
Virus Evol
. 2021 Aug;
7(1):veab031.
PMID: 34408913
is an important model for antiviral immunity in arthropods, but very few DNA viruses have been described from the family Drosophilidae. This deficiency limits our opportunity to use natural host-pathogen...
8.
Glaser-Schmitt A, Wittmann M, Ramnarine T, Parsch J
Mol Biol Evol
. 2021 Jul;
38(11):4891-4907.
PMID: 34289067
Understanding how genetic variation is maintained within species is a major goal of evolutionary genetics that can shed light on the preservation of biodiversity. Here, we examined the maintenance of...
9.
Belyi A, Argyridou E, Parsch J
Genome Biol Evol
. 2020 Oct;
12(12):2391-2402.
PMID: 33104185
Sex chromosomes often differ from autosomes with respect to their gene expression and regulation. In Drosophila melanogaster, X-linked genes are dosage compensated by having their expression upregulated in the male...
10.
Kapun M, Barron M, Staubach F, Obbard D, Wiberg R, Vieira J, et al.
Mol Biol Evol
. 2020 May;
37(9):2661-2678.
PMID: 32413142
Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of genetic variation in natural...