John Parsch
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Explore the profile of John Parsch including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Ramnarine T, Glaser-Schmitt A, Catalan A, Parsch J
Genes (Basel)
. 2019 Feb;
10(2).
PMID: 30769915
Although gene expression can vary extensively within and among populations, the genetic basis of this variation and the evolutionary forces that maintain it are largely unknown. In , a 49-bp...
12.
Glaser-Schmitt A, Zecic A, Parsch J
Genetics
. 2018 Jul;
210(1):287-301.
PMID: 29976765
Genetic variation influencing levels of gene expression is abundant in natural populations, and may exert its effects through complex mechanisms that depend on an organism's genetic background and the tissue...
13.
Argyridou E, Parsch J
Genes (Basel)
. 2018 May;
9(5).
PMID: 29734690
During the evolution of heteromorphic sex chromosomes, the sex-specific Y chromosome degenerates, while the X chromosome evolves new mechanisms of regulation. Using bioinformatic and experimental approaches, we investigate the expression...
14.
Glaser-Schmitt A, Parsch J
PLoS Biol
. 2018 Jan;
16(1):e2004538.
PMID: 29324742
Gene expression variation is a major contributor to phenotypic diversity within species and is thought to play an important role in adaptation. However, examples of adaptive regulatory polymorphism are rare,...
15.
Huylmans A, Lopez Ezquerra A, Parsch J, Cordellier M
Genome Biol Evol
. 2016 Sep;
8(10):3120-3139.
PMID: 27604882
Daphnia species have become models for ecological genomics and exhibit interesting features, such as high phenotypic plasticity and a densely packed genome with many lineage-specific genes. They are also cyclic...
16.
Grath S, Parsch J
Annu Rev Genet
. 2016 Aug;
50:29-44.
PMID: 27574843
Methods of transcriptional profiling have made it possible to compare gene expression between females and males on a genome-wide scale. Such studies have revealed that sex-biased gene expression is abundant...
17.
Catalan A, Glaser-Schmitt A, Argyridou E, Duchen P, Parsch J
PLoS Genet
. 2016 Apr;
12(4):e1005987.
PMID: 27120580
Insertions and deletions (indels) are a major source of genetic variation within species and may result in functional changes to coding or regulatory sequences. In this study we report that...
18.
Huylmans A, Parsch J
Genome Biol Evol
. 2015 Jun;
7(7):1960-71.
PMID: 26108491
Genes that are expressed differently between males and females (sex-biased genes) often show a nonrandom distribution in their genomic location, particularly with respect to the autosomes and the X chromosome....
19.
Huylmans A, Parsch J
G3 (Bethesda)
. 2014 Sep;
4(12):2307-15.
PMID: 25246242
Within species, levels of gene expression typically vary greatly between tissues, sexes, individuals, and populations. To investigate gene expression variation between sexes and populations in a single somatic tissue, we...
20.
Glaser-Schmitt A, Catalan A, Parsch J
Philos Trans R Soc Lond B Biol Sci
. 2013 Nov;
368(1632):20130024.
PMID: 24218636
As species colonize new habitats they must adapt to the local environment. Much of this adaptation is thought to occur at the regulatory level; however, the relationships among genetic polymorphism,...