John P Cortens
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Explore the profile of John P Cortens including associated specialties, affiliations and a list of published articles.
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10
Citations
523
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Recent Articles
1.
Keegan S, Cortens J, Beavis R, Fenyo D
J Proteome Res
. 2016 Feb;
15(3):983-90.
PMID: 26842767
Large scale proteomics have made it possible to broadly screen samples for the presence of many types of post-translational modifications, such as phosphorylation, acetylation, and ubiquitination. This type of data...
2.
Berard A, Cortens J, Krokhin O, Wilkins J, Severini A, Coombs K
PLoS One
. 2012 Dec;
7(12):e51939.
PMID: 23240068
All viruses are dependent upon host cells for replication. Infection can induce profound changes within cells, including apoptosis, morphological changes, and activation of signaling pathways. Many of these alterations have...
3.
Tran A, Cortens J, Du Q, Wilkins J, Coombs K
J Virol
. 2012 Nov;
87(2):1049-60.
PMID: 23135712
Influenza virus infection results in host cell death and major tissue damage. Specific components of the apoptotic pathway, a signaling cascade that ultimately leads to cell death, are implicated in...
4.
Turner-Brannen E, Choi K, Lippert D, Cortens J, Hancock R, El-Gabalawy H, et al.
Arthritis Res Ther
. 2011 Aug;
13(4):R129.
PMID: 21835002
Introduction: Innate defence regulator (IDR) peptides are synthetic cationic peptides, variants of naturally occurring innate immune effector molecules known as host defence peptides. IDR peptides were recently demonstrated to limit...
5.
Coombs K, Berard A, Xu W, Krokhin O, Meng X, Cortens J, et al.
J Virol
. 2010 Aug;
84(20):10888-906.
PMID: 20702633
Because they are obligate intracellular parasites, all viruses are exclusively and intimately dependent upon host cells for replication. Viruses, in turn, induce profound changes within cells, including apoptosis, morphological changes,...
6.
Dwivedi R, Krokhin O, Cortens J, Wilkins J
J Proteome Res
. 2009 Dec;
9(2):1144-9.
PMID: 20020779
The wide dynamic range of proteins in biological samples poses a challenge for the detection of low-abundance proteins. Recently, combinatorial hexapeptide peptide libraries have been suggested as an approach to...
7.
Ghosh D, Lippert D, Krokhin O, Cortens J, Wilkins J
J Mass Spectrom
. 2009 Dec;
45(1):1-25.
PMID: 19946888
The present study was initiated to define the composition of the membrane proteome of the Natural Killer (NK) like cell line YTS. Isolated membranes were treated with reagents that have...
8.
Krokhin O, Ying S, Cortens J, Ghosh D, Spicer V, Ens W, et al.
Anal Chem
. 2006 Sep;
78(17):6265-9.
PMID: 16944911
A new algorithm, sequence-specific retention calculator, was developed to predict retention time of tryptic peptides during RP HPLC fractionation on C18, 300-A pore size columns. Correlations of up to approximately...
9.
Craig R, Cortens J, Beavis R
Rapid Commun Mass Spectrom
. 2005 Jun;
19(13):1844-50.
PMID: 15945033
This paper describes an algorithm to apply proteotypic peptide sequence libraries to protein identifications performed using tandem mass spectrometry (MS/MS). Proteotypic peptides are those peptides in a protein sequence that...
10.
Craig R, Cortens J, Beavis R
J Proteome Res
. 2004 Dec;
3(6):1234-42.
PMID: 15595733
This paper describes an open-source system for analyzing, storing, and validating proteomics information derived from tandem mass spectrometry. It is based on a combination of data analysis servers, a user...