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John P Cannon

Explore the profile of John P Cannon including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1025
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Recent Articles
1.
Liberti A, Cannon J, Litman G, Dishaw L
Front Immunol . 2019 Mar; 10:369. PMID: 30894858
The gut microbiome of animals consists of diverse microorganisms that include both prokaryotes and eukaryotes. Complex interactions occur among these inhabitants, as well as with the immune system of the...
2.
Leigh B, Karrer C, Cannon J, Breitbart M, Dishaw L
Viruses . 2017 Mar; 9(3). PMID: 28327522
Outnumbering all other biological entities on earth, bacteriophages (phages) play critical roles in structuring microbial communities through bacterial infection and subsequent lysis, as well as through horizontal gene transfer. While...
3.
Dishaw L, Leigh B, Cannon J, Liberti A, Mueller M, Skapura D, et al.
Nat Commun . 2016 Feb; 7:10617. PMID: 26875669
Protochordate variable region-containing chitin-binding proteins (VCBPs) consist of immunoglobulin-type V domains and a chitin-binding domain (CBD). VCBP V domains facilitate phagocytosis of bacteria by granulocytic amoebocytes; the function of the...
4.
Liberti A, Leigh B, DE Santis R, Pinto M, Cannon J, Dishaw L, et al.
Results Probl Cell Differ . 2015 Nov; 57:159-73. PMID: 26537381
A variety of germline and somatic immune mechanisms have evolved in vertebrate and invertebrate species to detect a wide array of pathogenic invaders. The gut is a particularly significant site...
5.
Fahsbender E, Rosario K, Cannon J, Gulland F, Dishaw L, Breitbart M
Sci Rep . 2015 May; 5:9637. PMID: 25965294
New diseases in marine animals are emerging at an increasing rate, yet methodological limitations hinder characterization of viral infections. Viral metagenomics is an effective method for identifying novel viruses in...
6.
Dishaw L, Cannon J, Litman G, Parker W
Dev Comp Immunol . 2014 Jul; 47(1):36-51. PMID: 24984114
The animal gut serves as a primary location for the complex host-microbe interplay that is essential for homeostasis and may also reflect the types of ancient selective pressures that spawned...
7.
Kortum A, Rodriguez-Nunez I, Yang J, Shim J, Runft D, ODriscoll M, et al.
Immunogenetics . 2014 Jan; 66(4):267-79. PMID: 24469064
The polymeric immunoglobulin (Ig) receptor (pIgR) is an integral transmembrane glycoprotein that plays an important role in the mammalian immune response by transporting soluble polymeric Igs across mucosal epithelial cells....
8.
Amemiya C, Alfoldi J, Lee A, Fan S, Philippe H, MacCallum I, et al.
Nature . 2013 Apr; 496(7445):311-6. PMID: 23598338
The discovery of a living coelacanth specimen in 1938 was remarkable, as this lineage of lobe-finned fish was thought to have become extinct 70 million years ago. The modern coelacanth...
9.
Haire R, Cannon J, ODriscoll M, Ostrov D, Mueller M, Turner P, et al.
Genomics . 2012 Mar; 99(5):282-91. PMID: 22386706
A heretofore-unrecognized multigene family encoding diverse immunoglobulin (Ig) domain-containing proteins (DICPs) was identified in the zebrafish genome. Twenty-nine distinct loci mapping to three chromosomal regions encode receptor-type structures possessing two...
10.
Cannon J, ODriscoll M, Litman G
Immunogenetics . 2011 Jul; 64(1):39-47. PMID: 21800138
CD300, triggering receptor expressed on myeloid cells (TREM), and TREM-like (TREML) receptors are important regulators of the mammalian immune response. Homologs of these receptors, which occur in activating and inhibitory...