John Mudgett
Overview
Explore the profile of John Mudgett including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
341
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0
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Recent Articles
1.
Bouabout G, Ayme-Dietrich E, Jacob H, Champy M, Birling M, Pavlovic G, et al.
Arch Cardiovasc Dis
. 2017 Nov;
111(1):41-52.
PMID: 29113787
Background: Metabolic syndrome is a combination of symptoms including obesity, dyslipidaemia, glucose intolerance and hypertension. Oxidative stress appears to be a pathophysiological factor that links these signs and encourages progression...
2.
Guo Y, MacIsaac K, Chen Y, Miller R, Jain R, Joyce-Shaikh B, et al.
Cell Rep
. 2016 Dec;
17(12):3206-3218.
PMID: 28009290
Recent studies have elucidated the molecular mechanism of RORγT transcriptional regulation of Th17 differentiation and function. RORγT was initially identified as a transcription factor required for thymopoiesis by maintaining survival...
3.
Yang X, Mudgett J, Bou-About G, Champy M, Jacobs H, Monassier L, et al.
J Biol Chem
. 2016 Sep;
291(45):23428-23439.
PMID: 27621313
Mutations of the AMP-activated kinase gamma 2 subunit (AMPKγ2), N488I (AMPKγ2) and R531G (AMPKγ2), are associated with Wolff-Parkinson-White (WPW) syndrome, a cardiac disorder characterized by ventricular pre-excitation in humans. Cardiac-specific...
4.
Combe R, Mudgett J, Fertak L, Champy M, Ayme-Dietrich E, Petit-Demouliere B, et al.
PLoS One
. 2016 Apr;
11(4):e0153472.
PMID: 27088730
Background: Mouse transgenesis has provided the unique opportunity to investigate mechanisms underlying sodium kidney reabsorption as well as end organ damage. However, understanding mouse background and the experimental conditions effects...
5.
Derry J, Zhong H, Molony C, MacNeil D, GuhaThakurta D, Zhang B, et al.
PLoS One
. 2010 Dec;
5(12):e14319.
PMID: 21179467
To identify the genes and pathways that underlie cardiovascular and metabolic phenotypes we performed an integrated analysis of a mouse C57BL/6JxA/J F2 (B6AF2) cross by relating genome-wide gene expression data...
6.
Blom D, Yamin T, Champy M, Selloum M, Bedu E, Carballo-Jane E, et al.
Biochim Biophys Acta
. 2010 Sep;
1801(12):1349-60.
PMID: 20817122
The purinergic receptor P2Y(13) has been shown to play a role in the uptake of holo-HDL particles in in vitro hepatocyte experiments. In order to determine the role of P2Y(13)...
7.
Chen A, Mumick S, Zhang C, Lamb J, Dai H, Weingarth D, et al.
Obes Res
. 2005 Sep;
13(8):1311-20.
PMID: 16129712
Objective: To examine the effect of a high-fat diet on gene expression in adipose tissues and to determine induction kinetics of adipose monocyte chemoattractant protein-1 and -3 (MCP-1 and MCP-3)...
8.
McCawley L, Crawford H, King Jr L, Mudgett J, Matrisian L
Cancer Res
. 2004 Oct;
64(19):6965-72.
PMID: 15466188
Elevated expression of matrix metalloproteinase-3 (MMP-3/stromelysin-1) is associated with a variety of tumor types, although its in vivo functional role remains unclear. In human and murine squamous cell carcinoma (SCC),...
9.
Xie J, Nomura N, Lu M, Chen S, Koch G, Weng Y, et al.
J Leukoc Biol
. 2003 May;
73(6):771-80.
PMID: 12773510
Naïve T cells, when activated by specific antigen and cytokines, up-regulate adhesion molecules as well as chemokine receptors on their surface, which allows them to migrate to inflamed tissues. Human...