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John M Waechter Jr

Explore the profile of John M Waechter Jr including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 218
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Recent Articles
1.
Toner F, Allan G, Dimond S, Waechter Jr J, Beyer D
Toxicol In Vitro . 2017 Nov; 47:147-155. PMID: 29154941
Bisphenol A (BPA) is a high production volume compound. It is mainly used as a monomer to make polymers for various applications including food-contact materials. The primary route of exposure...
2.
Draganov D, Markham D, Beyer D, Waechter Jr J, Dimond S, Budinsky R, et al.
Toxicology . 2015 May; 333:168-178. PMID: 25929835
Orally administered bisphenol A (BPA) undergoes efficient first-pass metabolism to produce the inactive conjugates BPA-glucuronide (BPA-G) and BPA-sulfate (BPA-S). This study was conducted to evaluate the pharmacokinetics of BPA, BPA-G...
3.
Markham D, Waechter Jr J, Wimber M, Rao N, Connolly P, Chuang J, et al.
J Anal Toxicol . 2010 Jul; 34(6):293-303. PMID: 20663281
Bisphenol A (BPA) is an industrial chemical used to make polymers including some used in food contact applications. Virtually complete presystemic clearance of orally administered BPA occurs in humans by...
4.
Stump D, Beck M, Radovsky A, Garman R, Freshwater L, Sheets L, et al.
Toxicol Sci . 2010 Feb; 115(1):167-82. PMID: 20164145
This study was conducted to determine the potential of bisphenol A (BPA) to induce functional and/or morphological effects to the nervous system of F(1) offspring from dietary exposure during gestation...
5.
Tyl R, Myers C, Marr M, Sloan C, Castillo N, Veselica M, et al.
Toxicol Sci . 2008 May; 104(2):362-84. PMID: 18445619
Dietary bisphenol A (BPA) was evaluated in a mouse two-generation study at 0, 0.018, 0.18, 1.8, 30, 300, or 3500 ppm (0, 0.003, 0.03, 0.3, 5, 50, or 600 mg...
6.
Tyl R, Myers C, Marr M, Castillo N, Veselica M, Joiner R, et al.
Reprod Toxicol . 2008 Feb; 25(2):144-60. PMID: 18242050
There is no information on reproductive/developmental effects in mice from dietary estrogen. Therefore, 10 adult CD-1 mice/sex/group were administered dietary 17beta-estradiol (E2) at 0, 0.005, 0.05, 0.5, 2.5, 5, 10,...
7.
Tyl R, Myers C, Marr M, Sloan C, Castillo N, Veselica M, et al.
Toxicol Sci . 2008 Jan; 102(2):392-412. PMID: 18184636
No information exists on reproductive/developmental effects in mice exposed to dietary 17beta-estradiol (E2) over multiple generations. Therefore, under OECD Test Guideline 416 with enhancements, CD-1 mice (F0 generation, 25 mice/sex/group)...
8.
Spencer P, Gollapudi B, Waechter Jr J
Toxicol Sci . 2007 Mar; 97(1):120-7. PMID: 17329239
Doses of xenobiotics at or near LD50 may result in substantial hypothermia in mice. Hypothermia has previously been associated with an increase in micronuclei (MN) formation. The present series of...
9.
Teeguarden J, Waechter Jr J, Clewell 3rd H, Covington T, Barton H
Toxicol Sci . 2005 Mar; 85(2):823-38. PMID: 15746009
Bisphenol A (BPA) is a weakly estrogenic monomer used in the production of polycarbonate plastic and epoxy resins, both of which are used in food contact and other applications. A...