John M Dawes
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Explore the profile of John M Dawes including associated specialties, affiliations and a list of published articles.
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21
Citations
737
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Recent Articles
1.
Farah A, Patel R, Poplawski P, Wastie B, Tseng M, Barry A, et al.
Brain
. 2024 Sep;
148(3):1001-1014.
PMID: 39301592
Neuronal hyperexcitability is a key driver of persistent pain states, including neuropathic pain. Leucine-rich, glioma inactivated 1 (LGI1) is a secreted protein known to regulate excitability within the nervous system...
2.
Mountford R, Adler B, Andersson D, Bashford-Rogers R, Berwick R, Bevan S, et al.
Pain Rep
. 2024 Jun;
9(4):e1167.
PMID: 38873615
A 2-day closed workshop was held in Liverpool, United Kingdom, to discuss the results of research concerning symptom-based disorders (SBDs) caused by autoantibodies, share technical knowledge, and consider future plans....
3.
Daifallah O, Farah A, Dawes J
Front Mol Neurosci
. 2023 Dec;
16:1336871.
PMID: 38089675
[This corrects the article DOI: 10.3389/fnmol.2023.1254854.].
4.
Daifallah O, Farah A, Dawes J
Front Mol Neurosci
. 2023 Oct;
16:1254854.
PMID: 37799730
The immune system has a role in neuropathic pain which includes autoimmune mechanisms (e.g., autoantibodies). Clinical studies have identified a number of conditions where neuropathic pain is common and that...
5.
Middleton S, Perez-Sanchez J, Dawes J
J Anat
. 2021 Sep;
241(5):1186-1210.
PMID: 34528255
Primary sensory neurons are a heterogeneous population of cells able to respond to both innocuous and noxious stimuli. Like most neurons they are highly compartmentalised, allowing them to detect, convey...
6.
Dawes J, Bennett D
Neuron
. 2021 Sep;
109(17):2641-2642.
PMID: 34473950
Chronic pain is more common in women, however, our understanding of sex-specific differences in pain mechanisms is rudimentary. In this issue of Neuron, Luo et al., (2021) delineate a novel...
7.
Carroll L, Braeutigam S, Dawes J, Krsnik Z, Kostovic I, Coutinho E, et al.
Neuroscientist
. 2020 May;
27(1):10-29.
PMID: 32441222
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental disorders of genetic and environmental etiologies. Some ASD cases are syndromic: associated with clinically defined patterns of somatic abnormalities and...
8.
Baskozos G, Dawes J, Austin J, Antunes-Martins A, McDermott L, Clark A, et al.
Pain
. 2018 Oct;
160(2):463-485.
PMID: 30335683
Dorsal root ganglion (DRG) neurons provide connectivity between peripheral tissues and the spinal cord. Transcriptional plasticity within DRG sensory neurons after peripheral nerve injury contributes to nerve repair but also...
9.
Dawes J, Weir G, Middleton S, Patel R, Chisholm K, Pettingill P, et al.
Neuron
. 2018 Feb;
97(4):806-822.e10.
PMID: 29429934
Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum disorders, in which sensory dysfunction is increasingly recognized....
10.
Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by mutations
Sleigh J, Dawes J, West S, Wei N, Spaulding E, Gomez-Martin A, et al.
Proc Natl Acad Sci U S A
. 2017 Mar;
114(16):E3324-E3333.
PMID: 28351971
Charcot-Marie-Tooth disease type 2D (CMT2D) is a peripheral nerve disorder caused by dominant, toxic, gain-of-function mutations in the widely expressed, housekeeping gene, The mechanisms underlying selective nerve pathology in CMT2D...