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John L Waddington

Explore the profile of John L Waddington including associated specialties, affiliations and a list of published articles. Areas
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Articles 182
Citations 2101
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Yonemochi N, Nagase H, Waddington J, Ikeda H
Eur J Pharmacol . 2024 Oct; 984:177023. PMID: 39362391
Though μ and δ opioid receptors are reported to regulate energy homeostasis, any role for κ opioid receptors in these processes remains unclear. The present study investigated the role of...
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Waddington J, Wang X, Zhen X
Biomolecules . 2024 Sep; 14(9). PMID: 39334950
A wide array of biological abnormalities in psychotic illness appear to reflect non-cerebral involvement. This review first outlines the evidence for such a whole-body concept of schizophrenia pathobiology, focusing particularly...
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Sukno F, Kelly B, Lane A, Katina S, Rojas M, Whelan P, et al.
Psychiatry Res . 2024 Sep; 342:116213. PMID: 39326274
Development of the craniofacies occurs in embryological intimacy with development of the brain and both show normal left-right asymmetries. While facial dysmorphology occurs to excess in psychotic illness, facial asymmetry...
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Nkire N, Kinsella A, Russell V, Waddington J
Psychol Med . 2024 Sep; :1-3. PMID: 39324398
No abstract available.
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Yamagishi A, Yonemochi N, Kimura A, Takenoya F, Shioda S, Waddington J, et al.
Br J Pharmacol . 2024 Sep; 181(24):5028-5040. PMID: 39295124
Background And Purpose: Diabetic patients have an increased risk of psychiatric disorders. Because hyperglycaemia increases L-lactate in the brain and L-lactate inhibits AMP-activated protein kinase (AMPK), this study investigated the...
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Aono Y, Saito K, Kawashima H, Watanabe A, Kono T, Hashizume-Takizawa T, et al.
PLoS One . 2024 Jun; 19(6):e0292830. PMID: 38857232
Lipopolysaccharide (LPS), a component of the Gram-negative bacterial cell wall, activates Toll-like receptors (TLRs). Porphyromonas gingivalis (Pg) may be involved in the progression of periodontal disease. Mice exposed to a...
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Dawes C, McGreal S, Marwaha S, Prados J, Reheis A, Dumitrescu A, et al.
Schizophr Res Cogn . 2024 May; 37:100315. PMID: 38764742
Aberrant attentional salience has been implicated in the cannabis-psychosis association. Here, history and frequency of cannabis use were examined against changes in overshadowing (OS), a cue competition paradigm that involves...
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Zhang G, Zhu K, Li Q, Zhang Y, Waddington J, Du X, et al.
Acta Pharmacol Sin . 2024 Apr; 45(8):1582-1590. PMID: 38605179
SCH23390 is a widely used D dopamine receptor (DR) antagonist that also elicits some DR-independent effects. We previously found that the benzazepine, SKF83959, an analog of SCH23390, produces positive allosteric...
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