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John L Black 3rd

Explore the profile of John L Black 3rd including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 180
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Recent Articles
1.
Lopes J, Harris K, Karow M, Peterson S, Kluge M, Kotzer K, et al.
J Mol Diagn . 2022 Jan; 24(3):253-261. PMID: 35041929
Clinical pharmacogenomic testing typically uses targeted genotyping, which only detects variants included in the test design and may vary among laboratories. To evaluate the potential patient impact of genotyping compared...
2.
Moyer A, Dukek B, Duellman P, Schneider B, Wakefield L, Skierka J, et al.
Hum Immunol . 2020 Jun; 81(8):423-429. PMID: 32546429
We explored the feasibility of obtaining accurate HLA type using pre-existing NGS data not generated for HLA purposes. 83 exomes and 500 targeted NGS pharmacogenomic panels were analyzed using Omixon...
3.
Hooten W, Hu D, Cunningham J, Black 3rd J
Mol Pain . 2019 May; 15:1744806919848929. PMID: 31041874
The catechol-O-methyltransferase Val158Met polymorphism has been associated with alterations in pain perception, but the influence of the polymorphism on pain perception in patients with chronic pain receiving daily opioid therapy...
4.
St Sauver J, Olson J, Roger V, Nicholson W, Black 3rd J, Takahashi P, et al.
Pharmgenomics Pers Med . 2017 Aug; 10:217-227. PMID: 28769582
Background: Variation in the gene may affect response to opioids in both poor and ultrarapid metabolizers, but data demonstrating such associations have been mixed, and the impact of variants on...
5.
Langman L, Nesher L, Shah D, Azzi J, Shpall E, Rezvani K, et al.
J Mol Diagn . 2016 Jul; 18(5):638-642. PMID: 27371869
As part of a pharmacogenetic study, paired blood and oral fluid samples were tested for the IL28B polymorphism (rs12979860) before and after hematopoietic cell transplantation (HCT) to evaluate changes in...
6.
Ji Y, Skierka J, Blommel J, Moore B, VanCuyk D, Bruflat J, et al.
J Mol Diagn . 2016 Mar; 18(3):438-445. PMID: 26947514
Significant barriers, such as lack of professional guidelines, specialized training for interpretation of pharmacogenomics (PGx) data, and insufficient evidence to support clinical utility, prevent preemptive PGx testing from being widely...
7.
Avula R, OKane D, Black 3rd J
Biotechniques . 2014 Aug; 57(2):88-90. PMID: 25109294
5' nuclease assays for allelic discrimination use both a wild-type and a mutant probe. Here we present a new method for genotyping by 5' nuclease assays that dispenses with the...
8.
Black 3rd J, OKane D, Mrazek D
Expert Opin Drug Metab Toxicol . 2007 Feb; 3(1):21-31. PMID: 17269892
Psychiatric diseases that are treated with antidepressants are the leading causes of morbidity and mortality in humankind. Although antidepressants are generally well tolerated and widely available, they are not equally...
9.
Black 3rd J, Avula R, Walker D, Silber M, Krahn L, Pankratz V, et al.
Sleep . 2005 Nov; 28(9):1191-2. PMID: 16268389
No abstract available.
10.
Black 3rd J, Silber M, Krahn L, Fredrickson P, Pankratz V, Avula R, et al.
Sleep . 2005 Sep; 28(4):427-31. PMID: 16171287
Study Objectives: We tested the hypothesis that patients with narcolepsy have serum antibodies specific for preprohypocretin and its derivatives. Design: We tested sera from strictly diagnosed HLA DQB1*0602-positive narcoleptic patients...