John J Priatel
Overview
Explore the profile of John J Priatel including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
1001
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Recent Articles
1.
Matos I, Barvalia M, Chehal M, Robertson A, Kulic I, Silva J, et al.
Cancer Res Commun
. 2023 Mar;
3(3):404-419.
PMID: 36911097
Significance: Tumor-derived GCSF leads to systemic immune population changes. GCSF blockade restores immune populations, improves immunotherapy, and reduces tumor size, paralleling human colorectal cancer data. GCSF inhibition may synergize with...
2.
Biggs C, Cordeiro-Santanach A, Prykhozhij S, Deveau A, Lin Y, Del Bel K, et al.
JCI Insight
. 2022 Dec;
7(24).
PMID: 36546480
Primary atopic disorders are a group of inborn errors of immunity that skew the immune system toward severe allergic disease. Defining the biology underlying these extreme monogenic phenotypes reveals shared...
3.
Tsai K, Ma C, Han X, Allaire J, Lunken G, Crowley S, et al.
Cell Mol Gastroenterol Hepatol
. 2022 Oct;
15(2):425-438.
PMID: 36244647
Background & Aims: Increased intestinal permeability is seen in a variety of inflammatory conditions such as enteric infections and inflammatory bowel disease. Because barrier function can provide a key biomarker...
4.
Rijvers L, Melief M, van Langelaar J, van der Vuurst de Vries R, Wierenga-Wolf A, Koetzier S, et al.
J Immunol
. 2020 Jul;
205(4):945-956.
PMID: 32641384
C-type lectin is located next to , the master transcription factor of HLA class II (HLA-II), at a susceptibility locus for several autoimmune diseases, including multiple sclerosis (MS). We previously...
5.
Tsai K, Huang Y, Ma C, Baldwin T, Harder K, Vallance B, et al.
J Immunol
. 2020 Jun;
205(2):329-334.
PMID: 32540993
A layer of mucus functions to segregate contents of the intestinal lumen from the intestinal epithelium. The MUC2 mucin is the primary constituent of intestinal mucus and plays critical protective...
6.
Roberts M, Barvalia M, Silva J, Cederberg R, Chu W, Wong A, et al.
Circ Res
. 2020 Mar;
126(10):e61-e79.
PMID: 32151196
Rationale: Monocytes are key effectors of the mononuclear phagocyte system, playing critical roles in regulating tissue homeostasis and coordinating inflammatory reactions, including those involved in chronic inflammatory diseases such as...
7.
Bolger-Munro M, Choi K, Scurll J, Abraham L, Chappell R, Sheen D, et al.
Elife
. 2019 Jun;
8.
PMID: 31157616
When B cells encounter antigens on the surface of an antigen-presenting cell (APC), B cell receptors (BCRs) are gathered into microclusters that recruit signaling enzymes. These microclusters then move centripetally...
8.
Quancard J, Klein T, Fung S, Renatus M, Hughes N, Israel L, et al.
Nat Chem Biol
. 2019 Jan;
15(3):304-313.
PMID: 30692685
MALT1 paracaspase is central for lymphocyte antigen-dependent responses including NF-κB activation. We discovered nanomolar, selective allosteric inhibitors of MALT1 that bind by displacing the side chain of Trp580, locking the...
9.
Obach M, Hosseini-Tabatabaei A, Montane J, Wind K, Soukhatcheva G, Dai D, et al.
Mol Cell Endocrinol
. 2018 Jun;
477:48-56.
PMID: 29883690
Overexpression of the X-linked inhibitor of apoptosis (XIAP) prevents islet allograft rejection. We constructed an adeno-associated virus expressing XIAP driven by the rat insulin promoter (dsAAV8-RIP-XIAP) for long-term beta-cell gene...
10.
Lu H, Sharma M, Biggs C, Huang Y, Shopsowitz K, Frosk P, et al.
Pediatr Allergy Immunol
. 2018 May;
29(6):663-668.
PMID: 29808493
No abstract available.