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John J Murphy

Explore the profile of John J Murphy including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 743
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Recent Articles
1.
Murphy J, Surendranath K, Kanagaraj R
Int J Mol Sci . 2023 Jun; 24(11). PMID: 37298567
RNA-binding proteins (RBPs) represent a large family of proteins with an extensive array of roles that contribute to coordinating and directing multiple functions in RNA metabolism and transcription [...].
2.
Panchbhai A, Savash Ishanzadeh M, Sidali A, Solaiman N, Pankanti S, Kanagaraj R, et al.
Comput Methods Programs Biomed . 2023 Mar; 232:107447. PMID: 36889248
The cytokinesis block micronucleus assay is widely used for measuring/scoring/counting micronuclei, a marker of genome instability in cultured and primary cells. Though a gold standard method, this is a laborious...
3.
Saleem J, Wilck N, Murphy J, Herout J
Appl Clin Inform . 2022 May; 13(3):532-540. PMID: 35613912
Objective: The growing trend to use wearable devices to track activity and health data has the potential to positively impact the patient experience with their health care at home and...
4.
Sidali A, Teotia V, Solaiman N, Bashir N, Kanagaraj R, Murphy J, et al.
Int J Mol Sci . 2022 Jan; 23(1). PMID: 35008519
Genome integrity must be tightly preserved to ensure cellular survival and to deter the genesis of disease. Endogenous and exogenous stressors that impose threats to genomic stability through DNA damage...
5.
Davies T, Murphy J, Dousset M, Furstner A
J Am Chem Soc . 2021 Aug; 143(34):13489-13494. PMID: 34410708
Nickel catalysis allied with cyclodiphosphazane or VAPOL-derived phosphoramidite ligands provides selective access to monoprotected vicinal diols by reductive coupling of dienol ethers and aldehydes. The observed regioselectivity is unprecedented, in...
6.
Saleem J, Read J, Loehr B, Frisbee K, Wilck N, Murphy J, et al.
J Am Med Inform Assoc . 2020 May; 27(8):1300-1305. PMID: 32470974
The US Department of Veterans Affairs (VA) is using an automated short message service application named "Annie" as part of its coronavirus disease 2019 (COVID-19) response with a protocol for...
7.
Heinrich M, Murphy J, Ilg M, Letort A, Flasz J, Philipps P, et al.
J Am Chem Soc . 2020 Mar; 142(13):6409-6422. PMID: 32142305
The marine macrolide chagosensine is supposedly distinguished by a ()-configured 1,3-chlorodiene contained within a highly strained 16-membered lactone ring, which also incorporates two -2,5-disubstituted tetrahydrofuran (THF) rings; this array is...
8.
Rani A, Dasgupta P, Murphy J
Am J Pathol . 2019 Aug; 189(11):2119-2137. PMID: 31421072
Prostate cancer (PC) is a leading cause of death in men. Inflammation is one of the initiating processes whereby cells are trafficked into the tumor microenvironment by specific cytokines termed...
9.
Heinrich M, Murphy J, Ilg M, Letort A, Flasz J, Philipps P, et al.
Angew Chem Int Ed Engl . 2018 Aug; 57(41):13575-13581. PMID: 30152031
The marine macrolide chagosensine is the only natural product known to date that embodies a Z,Z-configured chloro-1,3-diene unit. This distinguishing substructure was prepared by a sequence of palladium-catalyzed 1,2-distannation of...
10.
Bahamonde A, Murphy J, Savarese M, Bremond E, Cavalli A, Melchiorre P
J Am Chem Soc . 2017 Mar; 139(12):4559-4567. PMID: 28281754
A combination of electrochemical, spectroscopic, computational, and kinetic studies has been used to elucidate the key mechanistic aspects of the previously reported enantioselective iminium ion trapping of photochemically generated carbon-centered...