John J Mullins
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Explore the profile of John J Mullins including associated specialties, affiliations and a list of published articles.
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125
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2668
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Recent Articles
11.
Assmus A, Mullins J, Brown C, Mullins L
Acta Physiol (Oxf)
. 2020 Jan;
229(1):e13447.
PMID: 31991057
Cellular plasticity is a topical subject with interest spanning a wide range of fields from developmental biology to regenerative medicine. Even the nomenclature is a subject of debate, and the...
12.
Taylor J, Nelson C, Bruton F, Kaveh A, Buckley C, Tucker C, et al.
Nat Commun
. 2019 Nov;
10(1):5173.
PMID: 31729395
Three-dimensional fluorescence time-lapse imaging of the beating heart is extremely challenging, due to the heart's constant motion and a need to avoid pharmacological or phototoxic damage. Although real-time triggered imaging...
13.
Lerman L, Kurtz T, Touyz R, Ellison D, Chade A, Crowley S, et al.
Hypertension
. 2019 Mar;
73(6):e87-e120.
PMID: 30866654
Hypertension is the most common chronic disease in the world, yet the precise cause of elevated blood pressure often cannot be determined. Animal models have been useful for unraveling the...
14.
Buckley C, Nelson R, Mullins L, Sharp M, Fleming S, Kenyon C, et al.
J Biol Chem
. 2017 Nov;
293(4):1151-1162.
PMID: 29123029
Normal renin synthesis and secretion is important for the maintenance of juxtaglomerular apparatus architecture. Mice lacking a functional gene are devoid of renal juxtaglomerular cell granules and exhibit an altered...
15.
Mills C, Lawrence M, Munro D, Elhendawi M, Mullins J, Davies J
Sci Rep
. 2017 Nov;
7(1):14824.
PMID: 29093551
We present a strategy for increasing the anatomical realism of organoids by applying asymmetric cues to mimic spatial information that is present in natural embryonic development, and demonstrate it using...
16.
Vliegenthart A, Wei C, Buckley C, Berends C, de Potter C, Schneemann S, et al.
Toxicol Sci
. 2017 Oct;
159(2):380-391.
PMID: 28962522
Triptolide is a vine extract used in traditional Chinese medicines and associated with hepatotoxicity. In vitro data suggest that inhibition of RNA synthesis may be the mechanism of toxicity. For...
17.
Menzies R, Zhao X, Mullins L, Mullins J, Cairns C, Wrobel N, et al.
Endocr Connect
. 2017 Jul;
6(7):446-457.
PMID: 28720595
Chronic ACTH exposure is associated with adrenal hypertrophy and steroidogenesis. The underlying molecular processes in mice have been analysed by microarray, histological and immunohistochemical techniques. Synacthen infused for 2 weeks...
18.
Menzies R, Booth J, Mullins J, Bailey M, Tam F, Norman J, et al.
EBioMedicine
. 2017 Apr;
19:73-83.
PMID: 28434946
Diabetes is a leading cause of renal disease. Glomerular mesangial expansion and fibrosis are hallmarks of diabetic nephropathy and this is thought to be promoted by infiltration of circulating macrophages....
19.
Tabriz A, Mills C, Mullins J, Davies J, Shu W
Front Bioeng Biotechnol
. 2017 Mar;
5:13.
PMID: 28286747
Development of a simple, straightforward 3D fabrication method to culture cells in 3D, without relying on any complex fabrication methods, remains a challenge. In this paper, we describe a new...
20.
Rider S, Christian H, Mullins L, Howarth A, MacRae C, Mullins J
Am J Physiol Renal Physiol
. 2017 Feb;
312(4):F778-F790.
PMID: 28179256
Zebrafish provide an excellent model in which to assess the role of the renin-angiotensin system in renal development, injury, and repair. In contrast to mammals, zebrafish kidney organogenesis terminates with...