John J Lemasters
Overview
Explore the profile of John J Lemasters including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
181
Citations
16898
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Liu X, Bian Z, Hu S, Dickinson C, Benjamin M, Jia J, et al.
Chem Rev
. 2024 Nov;
124(23):13099-13177.
PMID: 39571071
Phytoplankton have a high potential for CO capture and conversion. Besides being a vital food source at the base of oceanic and freshwater food webs, microalgae provide a critical platform...
2.
Hu J, Nieminen A, Zhong Z, Lemasters J
Livers
. 2024 Nov;
4(3):333-351.
PMID: 39554796
Overdose of acetaminophen (APAP) produces fulminant hepatic necrosis. The underlying mechanism of APAP hepatotoxicity involves mitochondrial dysfunction, including mitochondrial oxidant stress and the onset of mitochondrial permeability transition (MPT). Reactive...
3.
Savoca M, Takemoto K, Hu J, Li L, Jacob Kendrick B, Zhong Z, et al.
Biochem Biophys Res Commun
. 2024 Aug;
735:150457.
PMID: 39146811
Background: The liver lobule is divided into three zones or regions: periportal (PP or Zone 1) that is highly oxidative and active in ureagenesis, pericentral (PC or Zone 3) that...
4.
Samuvel D, Lemasters J, Chou C, Zhong Z
Front Pharmacol
. 2024 Jun;
15:1386238.
PMID: 38828459
Effective therapy for liver fibrosis is lacking. Here, we examined whether LP340, the lead candidate of a new-generation of hydrazide-based HDAC1,2,3 inhibitors (HDACi), decreases liver fibrosis. Liver fibrosis was induced...
5.
Carter J, Tsai M, Venturini N, Hu J, Lemasters J, Torres Martin M, et al.
Hepatology
. 2024 Feb;
80(3):566-577.
PMID: 38373106
Background And Aims: Sustained inflammation and hepatocyte injury in chronic liver disease activate HSCs to transdifferentiate into fibrogenic, contractile myofibroblasts. We investigated the role of protocadherin 7 (PCDH7), a cadherin...
6.
Karakaya E, Oleinik N, Edwards J, Tomberlin J, Barker R, Berber B, et al.
PNAS Nexus
. 2024 Feb;
3(2):pgae018.
PMID: 38328780
Repeat concussions (or repetitive mild traumatic brain injury [rmTBI]) are complex pathological processes consisting of a primary insult and long-term secondary complications and are also a prerequisite for chronic traumatic...
7.
Hu J, Nieminen A, Weemhoff J, Jaeschke H, Murphy L, Dent J, et al.
Toxicol Appl Pharmacol
. 2023 Oct;
479:116722.
PMID: 37848124
Acetaminophen (APAP) overdose disrupts hepatocellular lysosomes, which release ferrous iron (Fe) that translocates into mitochondria putatively via the mitochondrial calcium uniporter (MCU) to induce oxidative/nitrative stress, the mitochondrial permeability transition...
8.
Vitale I, Pietrocola F, Guilbaud E, Aaronson S, Abrams J, Adam D, et al.
Cell Death Differ
. 2023 Apr;
30(5):1097-1154.
PMID: 37100955
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have...
9.
Samuvel D, Krishnasamy Y, Li L, Lemasters J, Chou C, Zhong Z
RPS Pharm Pharmacol Rep
. 2023 Apr;
2(2):rqad013.
PMID: 37092117
Objectives: Some histone deacetylase (HDAC) isoforms contribute to ischaemia/reperfusion (IR) injury (IRI). Here, we examined whether LP342, the lead candidate of a new generation of hydrazide-based HDAC inhibitors (HDACi), decreases...
10.
Carson M, Warner A, Hathaway-Schrader J, Geiser V, Kim J, Gerasco J, et al.
JCI Insight
. 2022 Nov;
8(1).
PMID: 36413391
Antibiotic-induced shifts in the indigenous gut microbiota influence normal skeletal maturation. Current theory implies that gut microbiota actions on bone occur through a direct gut/bone signaling axis. However, our prior...