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John J Harada

Explore the profile of John J Harada including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 3491
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Recent Articles
1.
Pelletier J, Chen M, Lin J, Le B, Kirkbride R, Hur J, et al.
Proc Natl Acad Sci U S A . 2025 Jan; 122(1):e2416987121. PMID: 39793081
Seeds are complex structures composed of three regions, embryo, endosperm, and seed coat, with each further divided into subregions that consist of tissues, cell layers, and cell types. Although the...
2.
Jo L, Pelletier J, Goldberg R, Harada J
Proc Natl Acad Sci U S A . 2024 Oct; 121(45):e2415224121. PMID: 39475647
Understanding the regulatory mechanisms controlling storage lipid accumulation will inform strategies to enhance seed oil quality and quantity in crop plants. The WRINKLED1 transcription factor (WRI1 TF) is a central...
3.
Ruiz K, Pelletier J, Wang Y, Feng M, Behr J, ao T, et al.
Plant Direct . 2021 Oct; 5(10):e345. PMID: 34622120
Developmental transitions are typically tightly controlled at the transcriptional level. Two of these transitions involve the induction of the embryo maturation program midway through seed development and its repression during...
4.
Chen M, Lin J, Wu X, Apuya N, Henry K, Le B, et al.
Proc Natl Acad Sci U S A . 2021 Feb; 118(6). PMID: 33536344
An important question is what genes govern the differentiation of plant embryos into suspensor and embryo proper regions following fertilization and division of the zygote. We compared embryo proper and...
5.
Jo L, Pelletier J, Hsu S, Baden R, Goldberg R, Harada J
Proc Natl Acad Sci U S A . 2020 Jan; 117(2):1223-1232. PMID: 31892538
The LEAFY COTYLEDON1 (LEC1) transcription factor is a central regulator of seed development, because it controls diverse biological programs during seed development, such as embryo morphogenesis, photosynthesis, and seed maturation....
6.
Jo L, Pelletier J, Harada J
J Integr Plant Biol . 2019 Mar; 61(5):564-580. PMID: 30916433
Seed development is a complex period of the flowering plant life cycle. After fertilization, the three main regions of the seed, embryo, endosperm and seed coat, undergo a series of...
7.
Chen M, Lin J, Hur J, Pelletier J, Baden R, Pellegrini M, et al.
Proc Natl Acad Sci U S A . 2018 Aug; 115(35):E8315-E8322. PMID: 30104383
The precise mechanisms that control gene activity during seed development remain largely unknown. Previously, we showed that several genes essential for seed development, including those encoding storage proteins, fatty acid...
8.
Lin J, Le B, Chen M, Henry K, Hur J, Hsieh T, et al.
Proc Natl Acad Sci U S A . 2017 Oct; 114(45):E9730-E9739. PMID: 29078418
We profiled soybean and methylomes from the globular stage through dormancy and germination to understand the role of methylation in seed formation. CHH methylation increases significantly during development throughout the...
9.
Pelletier J, Kwong R, Park S, Le B, Baden R, Cagliari A, et al.
Proc Natl Acad Sci U S A . 2017 Jul; 114(32):E6710-E6719. PMID: 28739919
LEAFY COTYLEDON1 (LEC1), an atypical subunit of the nuclear transcription factor Y (NF-Y) CCAAT-binding transcription factor, is a central regulator that controls many aspects of seed development including the maturation...
10.
Douglass S, Hsu S, Cokus S, Goldberg R, Harada J, Pellegrini M
Plant J . 2016 Apr; 86(6):481-92. PMID: 27061965
MicroRNAs (miRNAs) are important regulatory molecules in eukaryotic organisms. Existing methods for the identification of mature miRNA sequences in plants rely extensively on the search for stem-loop structures, leading to...