Brandon H Le
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Explore the profile of Brandon H Le including associated specialties, affiliations and a list of published articles.
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21
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1033
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Recent Articles
1.
Jabbari P, Kim J, Le B, Zhang W, Zhang H, Martins-Green M
Antioxidants (Basel)
. 2025 Feb;
14(2).
PMID: 40002400
Chronic wounds (CWs) in humans affect millions of people in the US alone, cost billions of dollars, cause much suffering, and still there are no effective treatments. Patients seek medical...
2.
Kim J, Dong J, Le B, Lonergan Z, Gu W, Girke T, et al.
Antioxidants (Basel)
. 2024 Jun;
13(6).
PMID: 38929094
() is an opportunistic pathogen frequently isolated from cutaneous chronic wounds. How , in the presence of oxidative stress (OS), colonizes chronic wounds and forms a biofilm is still unknown....
3.
Ruggiero-Ruff R, Le B, Villa P, Lainez N, Athul S, Das P, et al.
Endocrinology
. 2023 Dec;
165(3).
PMID: 38146776
Obesity is a chronic disease with increasing prevalence worldwide. Obesity leads to an increased risk of heart disease, stroke, and diabetes, as well as endocrine alterations, reproductive disorders, changes in...
4.
Liu C, Le B, Xu W, Yang C, Chen Y, Zhao L
Nucleic Acids Res
. 2023 Jun;
51(13):e73.
PMID: 37293974
Mitochondrial DNA (mtDNA) modifications play an emerging role in innate immunity and inflammatory diseases. Nonetheless, relatively little is known regarding the locations of mtDNA modifications. Such information is critically important...
5.
Hwang Y, Han S, Yoo C, Hong L, You C, Le B, et al.
Nat Commun
. 2022 Dec;
13(1):7440.
PMID: 36460634
Light initiates chloroplast biogenesis in Arabidopsis by eliminating PHYTOCHROME-INTERACTING transcription FACTORs (PIFs), which in turn de-represses nuclear photosynthesis genes, and synchronously, generates a nucleus-to-plastid (anterograde) signal that activates the plastid-encoded...
6.
Wang Y, Le B, Wang J, You C, Zhao Y, Galli M, et al.
Sci Adv
. 2022 Nov;
8(47):eadc9454.
PMID: 36427317
In plants, RNA-directed DNA methylation (RdDM) uses small interfering RNAs (siRNAs) to target transposable elements (TEs) but usually avoids genes. RNA polymerase IV (Pol IV) shapes the landscape of DNA...
7.
Kong X, Yang M, Le B, He W, Hou Y
Mol Plant Pathol
. 2022 Jul;
23(10):1565-1574.
PMID: 35869407
Gene silencing mediated by small noncoding RNAs (sRNAs) is a fundamental gene regulation mechanism in eukaryotes that broadly governs cellular processes. It has been established that sRNAs are critical regulators...
8.
Gebiola M, Le B, Mauck K
Insect Sci
. 2022 Jan;
29(5):1318-1328.
PMID: 35068058
Transcriptomic studies are an important tool for understanding the molecular pathways underlying host plant use by agricultural pests, including vectors of damaging plant pathogens. Thus far, bulk RNA-Seq has been...
9.
Jia T, Le B
Bio Protoc
. 2021 Mar;
10(14):e3680.
PMID: 33659351
Steady-state mRNA levels are determined by both the rates of transcription and degradation. Regulation of mRNA stability and/or degradation are key factors that can significantly affect mRNA levels and its...
10.
Yu Y, Ji L, Le B, Zhai J, Chen J, Luscher E, et al.
PLoS Biol
. 2021 Feb;
19(2):e3001120.
PMID: 33571183
[This corrects the article DOI: 10.1371/journal.pbio.2001272.].