John Hazin
Overview
Explore the profile of John Hazin including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
450
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Recent Articles
1.
Eling N, Reuter L, Hazin J, Hamacher-Brady A, Brady N
Oncoscience
. 2015 Jun;
2(5):517-32.
PMID: 26097885
Oncogenic KRas reprograms pancreatic ductal adenocarcinoma (PDAC) cells to states which are highly resistant to apoptosis. Thus, a major preclinical goal is to identify effective strategies for killing PDAC cells....
2.
Hazin J, Moldenhauer G, Altevogt P, Brady N
J Immunol Methods
. 2015 May;
423:70-7.
PMID: 25967950
Monoclonal antibodies (mAbs) have emerged as a promising tool for cancer therapy. Differing approaches utilize mAbs to either deliver a drug to the tumor cells or to modulate the host's...
3.
Kiefel H, Bondong S, Hazin J, Ridinger J, Schirmer U, Riedle S, et al.
Cell Adh Migr
. 2012 Jul;
6(4):374-84.
PMID: 22796939
The L1 cell adhesion molecule (L1CAM) plays a major role in the development of the nervous system and in the malignancy of human tumors. In terms of biological function, L1CAM...
4.
Hauser S, Bickel L, Weinspach D, Gerg M, Schafer M, Pfeifer M, et al.
PLoS One
. 2011 May;
6(4):e18989.
PMID: 21541352
Tumour-specific splicing is known to contribute to cancer progression. In the case of the L1 cell adhesion molecule (L1CAM), which is expressed in many human tumours and often linked to...
5.
Kiefel H, Pfeifer M, Bondong S, Hazin J, Altevogt P
Trends Mol Med
. 2011 Jan;
17(4):178-87.
PMID: 21195665
The cell adhesion molecule L1 (L1CAM) was originally identified as a neural adhesion molecule essential for neurite outgrowth and axon guidance. Many studies have now shown that L1CAM is overexpressed...
6.
Gavert N, Vivanti A, Hazin J, Brabletz T, Ben-Zeev A
Mol Cancer Res
. 2010 Dec;
9(1):14-24.
PMID: 21123622
Aberrant activation of Wnt/β-catenin signaling is common in most sporadic and inherited colorectal cancer (CRC) cells leading to elevated β-catenin/TCF transactivation. We previously identified the neural cell adhesion molecule L1...