John H Owen
Overview
Explore the profile of John H Owen including associated specialties, affiliations and a list of published articles.
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10
Citations
251
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Recent Articles
1.
Walline H, Goudsmit C, McHugh J, Tang A, Owen J, Teh B, et al.
Head Neck
. 2017 Feb;
39(5):840-852.
PMID: 28236344
Background: Human papillomavirus (HPV)-positive oropharyngeal cancer is generally associated with excellent response to therapy, but some HPV-positive tumors progress despite aggressive therapy. The purpose of this study was to evaluate...
2.
Wang A, Owen J, Abuzeid W, Hervey-Jumper S, He X, Gurrea M, et al.
J Neurol Surg B Skull Base
. 2016 Nov;
77(6):510-520.
PMID: 27857879
Signal transducer and activator of transcription (STAT) proteins regulate key cellular fate decisions including proliferation and apoptosis. STAT3 overexpression induces tumor growth in multiple neoplasms. STAT3 is constitutively activated in...
3.
Owen J, Hauff S, Tang A, Graham M, Czerwinski M, Kaddoura M, et al.
Ann Otol Rhinol Laryngol
. 2014 May;
123(9):662-72.
PMID: 24816422
Objective: A new head and neck cancer cell line was developed from a highly aggressive HNSCC of the oral cavity diagnosed in a 26-year-old pregnant woman. Methods: Cells from the...
4.
Li Q, Lu L, Tao H, Xue C, Teitz-Tennenbaum S, Owen J, et al.
J Vis Exp
. 2014 Jan;
(83):e50561.
PMID: 24430104
We identified cancer stem cell (CSC)-enriched populations from murine melanoma D5 syngeneic to C57BL/6 mice and the squamous cancer SCC7 syngeneic to C3H mice using ALDEFLUOR/ALDH as a marker, and...
5.
Chinn S, Darr O, Owen J, Bellile E, McHugh J, Spector M, et al.
Head Neck
. 2014 Jan;
37(3):317-26.
PMID: 24415402
Background: Cancer stem cells (CSCs) represent a subpopulation of cells responsible for tumor growth. Their role in head and neck squamous cell carcinoma (HNSCC) tumorigenesis and metastasis remains uncertain. Methods:...
6.
Tang A, Owen J, Hauff S, Park J, Papagerakis S, Bradford C, et al.
Otolaryngol Head Neck Surg
. 2013 Apr;
149(2):252-60.
PMID: 23585151
Objectives: To determine if the behavior of cancer stem cells (CSCs) is affected by human papillomavirus (HPV) status. Study Design: An in vitro and in vivo analysis of HPV and...
7.
Czerwinski M, Desiderio V, Shkeir O, Papagerakis P, Lapadatescu M, Owen J, et al.
Otolaryngol Head Neck Surg
. 2013 Apr;
149(1):97-104.
PMID: 23558285
Objective: To evaluate in vitro the potential links between sialyl Lewis X (sLeX) and cancer stem cells (CSC) in head and neck squamous cell carcinoma (HNSCC). HNSCC is an aggressive...
8.
Tang A, Hauff S, Owen J, Graham M, Czerwinski M, Park J, et al.
Head Neck
. 2011 Dec;
34(10):1480-91.
PMID: 22162267
Background: Few human papillomavirus (HPV)(+) head and neck squamous cell carcinoma (HNSCC) cell lines exist. We established University of Michigan-squamous cell carcinoma-104 (UM-SCC-104), a new HPV(+) HNSCC cell line from...
9.
Tabor M, Clay M, Owen J, Bradford C, Carey T, Wolf G, et al.
Laryngoscope
. 2011 Feb;
121(3):527-33.
PMID: 21344428
Objectives/hypothesis: The cancer stem cell (CSC) theory concludes that a subpopulation of cancer cells, the cancer stem cells, can self-renew and are responsible for tumor growth. Previous studies have identified...
10.
Davis S, Divi V, Owen J, Bradford C, Carey T, Papagerakis S, et al.
Arch Otolaryngol Head Neck Surg
. 2010 Dec;
136(12):1260-6.
PMID: 21173377
Objective: to design in vitro and in vivo models of metastasis to study the behavior of cancer stem cells (CSCs) in head and neck squamous cell carcinoma (HNSCC). Design: cells...