John H Kersey
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Explore the profile of John H Kersey including associated specialties, affiliations and a list of published articles.
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22
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Recent Articles
11.
Tomblyn M, Arora M, Baker K, Blazar B, Brunstein C, Burns L, et al.
J Clin Oncol
. 2009 Jul;
27(22):3634-41.
PMID: 19581540
Purpose: Analysis of hematopoietic cell transplantation (HCT) for high-risk or recurrent acute lymphoblastic leukemia (ALL) using different donor sources is confounded by variable conditioning and supportive care. Patients And Methods:...
12.
Kumar A, Li Q, Hudson W, Chen W, Sam T, Yao Q, et al.
Blood
. 2008 Dec;
113(8):1756-8.
PMID: 19109563
Leukemias with MLL rearrangements are characterized by high expression of the homeobox gene MEIS1. In these studies, we knocked down Meis1 expression by shRNA lentivirus transduction in murine Mll-AF9 leukemia...
13.
Chen W, Kumar A, Hudson W, Li Q, Wu B, Staggs R, et al.
Cancer Cell
. 2008 May;
13(5):432-40.
PMID: 18455126
The pathways by which oncogenes, such as MLL-AF9, initiate transformation and leukemia in humans and mice are incompletely defined. In a study of target cells and oncogene dosage, we found...
14.
Kersey J
Immunol Res
. 2007 Oct;
38(1-3):149-64.
PMID: 17917022
On the occasion of the first meeting of the Robert A. Good Immunology Society in June of 2006, I was asked to provide a perspective on the history and progress...
15.
Chen W, Li Q, Hudson W, Kumar A, Kirchhof N, Kersey J
Blood
. 2006 Mar;
108(2):669-77.
PMID: 16551973
The 2 most frequent human MLL hematopoietic malignancies involve either AF4 or AF9 as fusion partners; each has distinct biology but the role of the fusion partner is not clear....
16.
Muyrers-Chen I, Rozovskaia T, Lee N, Kersey J, Nakamura T, Canaani E, et al.
Oncogene
. 2004 Sep;
23(53):8639-48.
PMID: 15378024
The Mixed Lineage Leukemia (MLL) gene is involved in lymphoblastic and myeloid leukemia through chromosome translocations leading to fusion of MLL to partner genes, or through internal MLL rearrangements. MLL...
17.
Radiotherapy of CD19 expressing Daudi tumors in nude mice with Yttrium-90-labeled anti-CD19 antibody
Vallera D, Elson M, Brechbiel M, Dusenbery K, Burns L, Jaszcz W, et al.
Cancer Biother Radiopharm
. 2004 Apr;
19(1):11-23.
PMID: 15068607
Studies were performed to determine the suitability of using two different anti-CD19 monoclonal antibodies to deliver the high energy beta-particle emitting isotope 90Y to B-cell lymphoma grown as flank tumors...
18.
Kumar A, Hudson W, Chen W, Nishiuchi R, Yao Q, Kersey J
Blood
. 2003 Nov;
103(5):1823-8.
PMID: 14615372
Identification of the targets of mixed lineage leukemia (MLL) fusion genes will assist in understanding the biology of MLL fusion gene leukemias and in development of better therapies. Numerous studies...
19.
Yao Q, Nishiuchi R, Li Q, Kumar A, Hudson W, Kersey J
Clin Cancer Res
. 2003 Oct;
9(12):4483-93.
PMID: 14555522
Purpose: We conducted studies to evaluate the hypothesis that FLT3 is a client of heat shock protein (Hsp) 90 and inhibitors of Hsp90 may be useful for therapy of leukemia....
20.
Armstrong S, Kung A, Mabon M, Silverman L, Stam R, den Boer M, et al.
Cancer Cell
. 2003 Mar;
3(2):173-83.
PMID: 12620411
We recently found that MLL-rearranged acute lymphoblastic leukemias (MLL) have a unique gene expression profile including high level expression of the receptor tyrosine kinase FLT3. We hypothesized that FLT3 might...