John F Kearney
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Explore the profile of John F Kearney including associated specialties, affiliations and a list of published articles.
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75
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2704
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Recent Articles
11.
New J, King R, Kearney J
Viral Immunol
. 2019 Dec;
33(4):266-276.
PMID: 31851873
Adaptive antibody responses provide a crucial means of host defense against viral infections by mediating the neutralization and killing infectious pathogens. At the forefront of humoral defense against viruses lie...
12.
Matthews D, Kearney J, Cromie A, Hely F, Amer P
Genet Sel Evol
. 2019 Jul;
51(1):40.
PMID: 31311493
Background: In modern dairy breeding programmes, high contributions from foreign sires are nearly always present. Genotyping, and therefore genomic selection (GS), concern only a subpopulation of the breeding programme's wider...
13.
Komarova B, Wong S, Orekhova M, Tsvetkov Y, Krylov V, Beauvais A, et al.
J Org Chem
. 2018 Oct;
83(21):12965-12976.
PMID: 30277398
Biotinylated hepta-, nona- and undeca-α-(1 → 3)-d-glucosides representing long oligosaccharides of α-(1 → 3)-d-glucan, one of the major components of the cell walls of the fungal pathogen Aspergillus fumigatus, were...
14.
Dickinson G, Levenson E, Walker J, Kearney J, Alugupalli K
J Immunol
. 2018 Jul;
201(4):1229-1240.
PMID: 30006375
Polysaccharide vaccines such as the Vi polysaccharide (ViPS) of serovar Typhi induce efficient Ab responses in adults but not in young children. The reasons for this difference are not understood....
15.
Belde V, Cravens M, Gulandijany D, Walker J, Palomo-Caturla I, Alugupalli A, et al.
Infect Immun
. 2018 Jul;
86(9).
PMID: 29967094
B cell antigen receptor (BCR) diversity increases by several orders of magnitude due to the action of terminal deoxynucleotidyl transferase (TdT) during V(D)J recombination. Unlike adults, infants have limited BCR...
16.
Wang Y, Schafer C, Hough K, Tousif S, Duncan S, Kearney J, et al.
J Immunol
. 2018 May;
201(1):278-295.
PMID: 29752311
Myeloid-derived suppressor cells (MDSCs) are known suppressors of antitumor immunity, affecting amino acid metabolism and T cell function in the tumor microenvironment. However, it is unknown whether MDSCs regulate B...
17.
McClure M, McCarthy J, Flynn P, McClure J, Dair E, OConnell D, et al.
Front Genet
. 2018 Mar;
9:84.
PMID: 29599798
A major use of genetic data is parentage verification and identification as inaccurate pedigrees negatively affect genetic gain. Since 2012 the international standard for single nucleotide polymorphism (SNP) verification in...
18.
Browett S, McHugo G, Richardson I, Magee D, Park S, Fahey A, et al.
Front Genet
. 2018 Mar;
9:51.
PMID: 29520297
Kerry cattle are an endangered landrace heritage breed of cultural importance to Ireland. In the present study we have used genome-wide SNP array data to evaluate genomic diversity within the...
19.
McDonald G, Medina C, Pilichowska M, Kearney J, Shinkura R, Selsing E, et al.
Front Immunol
. 2017 Sep;
8:1094.
PMID: 28955333
564Igi mice have knocked-in immunoglobulin (Ig) heavy (H) and light (L) chain genes that encode an autoantibody recognizing RNA. Previously, we showed that these mice produce pathogenic IgG autoantibodies when...
20.
Azzam K, Madenspacher J, Cain D, Lai L, Gowdy K, Rai P, et al.
JCI Insight
. 2017 Aug;
2(16).
PMID: 28814662
The pathogenesis of primary Sjogren's syndrome (SS), an autoimmune disease that targets the mucosa of exocrine tissues, is poorly understood. Although several mouse models have been developed that display features...