John E Landers
Overview
Explore the profile of John E Landers including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
94
Citations
4375
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Iacoangeli A, Dilliott A, Al Khleifat A, Andersen P, Basak N, Cooper-Knock J, et al.
J Neurol Neurosurg Psychiatry
. 2025 Feb;
PMID: 39947885
Background: Despite several studies suggesting a potential oligogenic risk model in amyotrophic lateral sclerosis (ALS), case-control statistical evidence implicating oligogenicity with disease risk or clinical outcomes is limited. Considering its...
2.
Grant O, Iacoangeli A, Zwamborn R, van Rheenen W, Byrne R, van Eijk K, et al.
bioRxiv
. 2024 Dec;
PMID: 39651197
Sex is an important covariate in all genetic and epigenetic research due to its role in the incidence, progression and outcome of many phenotypic characteristics and human diseases. Amyotrophic lateral...
3.
Saez-Atienzar S, Souza C, Chia R, Beal S, Lorenzini I, Huang R, et al.
Cell Genom
. 2024 Oct;
4(11):100679.
PMID: 39437787
Repeat expansions in the C9orf72 gene are the most common genetic cause of (ALS) and frontotemporal dementia (FTD). Like other genetic forms of neurodegeneration, pinpointing the precise mechanism(s) by which...
4.
Opie-Martin S, Iacoangeli A, Topp S, Abel O, Mayl K, Mehta P, et al.
Nat Commun
. 2024 Jul;
15(1):5560.
PMID: 38956107
No abstract available.
5.
Hop P, Lai D, Keagle P, Baron D, Kenna B, Kooyman M, et al.
Nat Genet
. 2024 Jun;
56(7):1371-1376.
PMID: 38858457
Despite substantial progress, causal variants are identified only for a minority of familial Parkinson's disease (PD) cases, leaving high-risk pathogenic variants unidentified. To identify such variants, we uniformly processed exome...
6.
Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS
Marriott H, Spargo T, Al Khleifat A, Andersen P, Basak N, Cooper-Knock J, et al.
Ann Clin Transl Neurol
. 2024 May;
11(7):1775-1786.
PMID: 38775181
Objective: Neurofilament heavy-chain gene (NEFH) variants are associated with multiple neurodegenerative diseases, however, their relationship with ALS has not been robustly explored. Still, NEFH is commonly included in genetic screening...
7.
Funes S, Jung J, Gadd D, Mosqueda M, Zhong J, Shankaracharya , et al.
Nat Commun
. 2024 Mar;
15(1):2497.
PMID: 38509062
Microglia play a pivotal role in neurodegenerative disease pathogenesis, but the mechanisms underlying microglia dysfunction and toxicity remain to be elucidated. To investigate the effect of neurodegenerative disease-linked genes on...
8.
Mann J, Mckenna E, Mawrie D, Papakis V, Alessandrini F, Anderson E, et al.
Sci Adv
. 2023 Aug;
9(33):eadi5548.
PMID: 37585529
Loss-of-function variants in NIMA-related kinase 1 (NEK1) constitute a major genetic cause of amyotrophic lateral sclerosis (ALS), accounting for 2 to 3% of all cases. However, how mutations cause motor...
9.
Funes S, Gadd D, Mosqueda M, Zhong J, Jung J, Shankaracharya , et al.
bioRxiv
. 2023 Jul;
PMID: 37398081
Microglia play a pivotal role in neurodegenerative disease pathogenesis, but the mechanisms underlying microglia dysfunction and toxicity remain to be fully elucidated. To investigate the effect of neurodegenerative disease-linked genes...
10.
Kaivola K, Chia R, Ding J, Rasheed M, Fujita M, Menon V, et al.
Cell Genom
. 2023 Jun;
3(6):100316.
PMID: 37388914
We characterized the role of structural variants, a largely unexplored type of genetic variation, in two non-Alzheimer's dementias, namely Lewy body dementia (LBD) and frontotemporal dementia (FTD)/amyotrophic lateral sclerosis (ALS)....