John E Donelson
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Explore the profile of John E Donelson including associated specialties, affiliations and a list of published articles.
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39
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2085
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Recent Articles
1.
Yao C, Dixit U, Barker J, Teesch L, Love-Homan L, Donelson J, et al.
Infect Immun
. 2013 May;
81(7):2507-17.
PMID: 23630964
The infectious metacyclic promastigotes of Leishmania protozoa establish infection in a mammalian host after they are deposited into the dermis by a sand fly vector. Several Leishmania virulence factors promote...
2.
Weirather J, Wilson M, Donelson J
Mol Biochem Parasitol
. 2011 Nov;
181(2):141-52.
PMID: 22079099
The protozoan parasite Trypanosoma brucei switches its variant surface glycoprotein (VSG) to subvert its mammalian hosts' immune responses. The T. brucei genome contains as many as 1600 VSG genes (VSGs),...
3.
Weirather J, Jeronimo S, Gautam S, Sundar S, Kang M, Kurtz M, et al.
J Clin Microbiol
. 2011 Nov;
49(11):3892-904.
PMID: 22042830
The Leishmania species cause a variety of human disease syndromes. Methods for diagnosis and species differentiation are insensitive and many require invasive sampling. Although quantitative PCR (qPCR) methods are reported...
4.
Hsiao C, Ueno N, Shao J, Schroeder K, Moore K, Donelson J, et al.
Microbes Infect
. 2011 Jul;
13(12-13):1033-44.
PMID: 21723411
Leishmania spp. protozoa are obligate intracellular parasites that replicate in macrophages during mammalian infection. Efficient phagocytosis and survival in macrophages are important determinants of parasite virulence. Macrophage lines differ dramatically...
5.
Eyford B, Sakurai T, Smith D, Loveless B, Hertz-Fowler C, Donelson J, et al.
Mol Biochem Parasitol
. 2011 Mar;
177(2):116-25.
PMID: 21354217
Trypanosoma congolense is an important pathogen of livestock in Africa. To study protein expression throughout the T. congolense life cycle, we used culture-derived parasites of each of the three main...
6.
Yao C, Li Y, Donelson J, Wilson M
Proteomics Clin Appl
. 2010 Dec;
4(1):4-16.
PMID: 21137013
Purpose: About two million new cases of leishmaniasis with 50 000 associated deaths occur worldwide each year. Promastigotes of the causative Leishmania spp. develop from the procyclic stage to the...
7.
Leishmania infantum chagasi: a genome-based approach to identification of excreted/secreted proteins
DebRoy S, Keenan A, Ueno N, Jeronimo S, Donelson J, Wilson M
Exp Parasitol
. 2010 Jun;
126(4):582-91.
PMID: 20542033
The parasitic protozoan, Leishmania, survives in harsh environments within its mammalian and sand fly hosts. Secreted proteins likely play critical roles in the parasite's interactions with its environment. As a...
8.
Helm J, Hertz-Fowler C, Aslett M, Berriman M, Sanders M, Quail M, et al.
Mol Biochem Parasitol
. 2009 Jun;
168(1):34-42.
PMID: 19559733
Trypanosoma congolense is one of the most economically important pathogens of livestock in Africa. Culture-derived parasites of each of the three main insect stages of the T. congolense life cycle,...
9.
Helm J, Wilson M, Donelson J
Mol Biochem Parasitol
. 2008 Oct;
163(1):8-18.
PMID: 18848586
During their life cycle African trypanosomes must quickly adapt to the different environments of the tsetse fly midgut and the mammalian bloodstream by modulating expression of many of their genes....
10.
Helm J, Wilson M, Donelson J
Mol Biochem Parasitol
. 2008 Apr;
159(2):134-7.
PMID: 18384893
Most trypanosomatid genes are transcribed into polycistronic precursor RNAs that are processed into monocistronic mRNAs possessing a 39-nucleotide spliced leader (SL) at their 5'-ends and polyadenylation at their 3'-ends. We...