John E Baenziger
Overview
Explore the profile of John E Baenziger including associated specialties, affiliations and a list of published articles.
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45
Citations
735
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Recent Articles
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Nys M, Zarkadas E, Brams M, Mehregan A, Kambara K, Kool J, et al.
Nat Commun
. 2024 May;
15(1):4532.
PMID: 38806512
No abstract available.
3.
Ananchenko A, Gao R, Dehez F, Baenziger J
Commun Biol
. 2024 Apr;
7(1):437.
PMID: 38600247
The ability of the Torpedo nicotinic acetylcholine receptor (nAChR) to undergo agonist-induced conformational transitions requires the presence of cholesterol and/or anionic lipids. Here we use recently solved structures along with...
4.
Thompson M, Bekarkhanechi F, Ananchenko A, Nury H, Baenziger J
Nat Commun
. 2024 Feb;
15(1):1803.
PMID: 38413583
Synaptic receptors respond to neurotransmitters by opening an ion channel across the post-synaptic membrane to elicit a cellular response. Here we use recent Torpedo acetylcholine receptor structures and functional measurements...
5.
Slobodyanyuk M, Banda-Vazquez J, Thompson M, Dean R, Baenziger J, Chica R, et al.
Commun Biol
. 2022 Nov;
5(1):1264.
PMID: 36400839
ELIC is a prokaryotic homopentameric ligand-gated ion channel that is homologous to vertebrate nicotinic acetylcholine receptors. Acetylcholine binds to ELIC but fails to activate it, despite bringing about conformational changes...
6.
Nys M, Zarkadas E, Brams M, Mehregan A, Kambara K, Kool J, et al.
Nat Commun
. 2022 Aug;
13(1):4543.
PMID: 35927270
Bites by elapid snakes (e.g. cobras) can result in life-threatening paralysis caused by venom neurotoxins blocking neuromuscular nicotinic acetylcholine receptors. Here, we determine the cryo-EM structure of the muscle-type Torpedo...
7.
Ananchenko A, Hussein T, Mody D, Thompson M, Baenziger J
Biomolecules
. 2022 Jun;
12(6).
PMID: 35740939
Pentameric ligand-gated ion channels (pLGICs) play a leading role in synaptic communication, are implicated in a variety of neurological processes, and are important targets for the treatment of neurological and...
8.
Thompson M, Domville J, Edrington C, Venes A, Giguere P, Baenziger J
J Biol Chem
. 2022 Jun;
298(7):102104.
PMID: 35679899
The outermost lipid-exposed α-helix (M4) in each of the homologous α, β, δ, and γ/ε subunits of the muscle nicotinic acetylcholine receptor (nAChR) has previously been proposed to act as...
9.
Baenziger J, Ananchenko A, Hussein T, Mody D
Biophys Rev
. 2022 Jan;
13(6):871-873.
PMID: 35059011
No abstract available.
10.