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John D Potter

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Articles 454
Citations 16062
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Recent Articles
1.
Bagshaw P, Bagshaw S, Potter J, Hornblow A, Nicholls M, Shaw C
N Z Med J . 2024 Sep; 137(1602):143-144. PMID: 39236334
No abstract available.
2.
Drew D, Kim A, Lin Y, Qu C, Morrison J, Lewinger J, et al.
Sci Adv . 2024 May; 10(22):eadk3121. PMID: 38809988
Regular, long-term aspirin use may act synergistically with genetic variants, particularly those in mechanistically relevant pathways, to confer a protective effect on colorectal cancer (CRC) risk. We leveraged pooled data...
3.
Papadimitriou N, Kim A, Kawaguchi E, Morrison J, Diez-Obrero V, Albanes D, et al.
EBioMedicine . 2024 May; 104:105146. PMID: 38749303
Background: Consumption of fibre, fruits and vegetables have been linked with lower colorectal cancer (CRC) risk. A genome-wide gene-environment (G × E) analysis was performed to test whether genetic variants...
4.
Chen Z, Guo X, Tao R, Huyghe J, Law P, Fernandez-Rozadilla C, et al.
Nat Commun . 2024 Apr; 15(1):3557. PMID: 38670944
Genome-wide association studies (GWAS) have identified more than 200 common genetic variants independently associated with colorectal cancer (CRC) risk, but the causal variants and target genes are mostly unknown. We...
5.
Tian Y, Lin Y, Qu C, Arndt V, Baurley J, Berndt S, et al.
Br J Cancer . 2024 Apr; 130(10):1687-1696. PMID: 38561434
Background: Menopausal hormone therapy (MHT), a common treatment to relieve symptoms of menopause, is associated with a lower risk of colorectal cancer (CRC). To inform CRC risk prediction and MHT...
6.
Song Y, Loomans-Kropp H, Baugher R, Somerville B, Baxter S, Kerr T, et al.
J Natl Cancer Inst . 2024 Mar; 116(6):957-965. PMID: 38466935
Background: Lynch syndrome is a hereditary cancer predisposition syndrome caused by germline mutations in DNA mismatch repair genes, which lead to high microsatellite instability and frameshift mutations at coding mononucleotide...
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Burnett-Hartman A, Ton M, He Q, Malen R, Potter J, Reedy A, et al.
Nutr Cancer . 2024 Feb; 76(4):352-355. PMID: 38347682
We aimed to evaluate differences in dietary factors between young-onset (diagnosed at ages <50) and older-onset colorectal cancer (CRC). CRC patients diagnosed from 1998 to 2018 reported to the Puget...
9.
Nimptsch K, Aleksandrova K, Pham T, Papadimitriou N, Janke J, Christakoudi S, et al.
BMC Med . 2023 Oct; 21(1):391. PMID: 37833736
Background: Fatty acid binding protein 4 (FABP-4) is a lipid-binding adipokine upregulated in obesity, which may facilitate fatty acid supply for tumor growth and promote insulin resistance and inflammation and...
10.
Thomas M, Su Y, Rosenthal E, Sakoda L, Schmit S, Timofeeva M, et al.
Nat Commun . 2023 Oct; 14(1):6147. PMID: 37783704
Polygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European ancestry...