John C Silbereis
Overview
Explore the profile of John C Silbereis including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
1066
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0
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Recent Articles
1.
Sabo J, Heine V, Silbereis J, Schirmer L, Levison S, Rowitch D
Ann Neurol
. 2017 Mar;
81(4):560-571.
PMID: 28253550
Objective: Neonatal white matter injury (NWMI) is a lesion found in preterm infants that can lead to cerebral palsy. Although antagonists of bone morphogenetic protein (BMP) signaling, such as Noggin,...
2.
Olmos-Serrano J, Kang H, Tyler W, Silbereis J, Cheng F, Zhu Y, et al.
Neuron
. 2016 Mar;
89(6):1208-1222.
PMID: 26924435
Trisomy 21, or Down syndrome (DS), is the most common genetic cause of developmental delay and intellectual disability. To gain insight into the underlying molecular and cellular pathogenesis, we conducted...
3.
Silbereis J, Pochareddy S, Zhu Y, Li M, Sestan N
Neuron
. 2016 Jan;
89(2):248-68.
PMID: 26796689
The human CNS follows a pattern of development typical of all mammals, but certain neurodevelopmental features are highly derived. Building the human CNS requires the precise orchestration and coordination of...
4.
Yuen T, Silbereis J, Griveau A, Chang S, Daneman R, Fancy S, et al.
Cell
. 2014 Jul;
158(2):383-396.
PMID: 25018103
Myelin sheaths provide critical functional and trophic support for axons in white matter tracts of the brain. Oligodendrocyte precursor cells (OPCs) have extraordinary metabolic requirements during development as they differentiate...
5.
Fancy S, Harrington E, Baranzini S, Silbereis J, Shiow L, Yuen T, et al.
Nat Neurosci
. 2014 Mar;
17(4):506-12.
PMID: 24609463
In colon cancer, mutation of the Wnt repressor APC (encoding adenomatous polyposis coli) leads to a state of aberrant and unrestricted high-activity signaling. However, the relevance of high Wnt tone...
6.
Silbereis J, Nobuta H, Tsai H, Heine V, McKinsey G, Meijer D, et al.
Neuron
. 2014 Feb;
81(3):574-87.
PMID: 24507192
Abnormal GABAergic interneuron density, and imbalance of excitatory versus inhibitory tone, is thought to result in epilepsy, neurodevelopmental disorders, and psychiatric disease. Recent studies indicate that interneuron cortical density is...
7.
Fancy S, Harrington E, Yuen T, Silbereis J, Zhao C, Baranzini S, et al.
Nat Neurosci
. 2011 Jun;
14(8):1009-16.
PMID: 21706018
Permanent damage to white matter tracts, comprising axons and myelinating oligodendrocytes, is an important component of brain injuries of the newborn that cause cerebral palsy and cognitive disabilities, as well...
8.
Silbereis J, Huang E, Back S, Rowitch D
Dis Model Mech
. 2010 Oct;
3(11-12):678-88.
PMID: 21030421
Newborn neurological injuries are the leading cause of intellectual and motor disabilities that are associated with cerebral palsy. Cerebral white matter injury is a common feature in hypoxic-ischemic encephalopathy (HIE),...