John C Sembrat
Overview
Explore the profile of John C Sembrat including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
269
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Rao R, Yang J, Jiang S, El-Khoury W, Hafeez N, Okawa S, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Dec;
328(1):L148-L158.
PMID: 39657959
Pulmonary arterial hypertension (PAH) is a progressive disease driven by endothelial cell inflammation and dysfunction, resulting in the pathological remodeling of the pulmonary vasculature. Innate immune activation has been linked...
2.
Iasella C, Hannan S, Lyons E, Lieber S, Das A, Dimitrov D, et al.
PLoS One
. 2024 Oct;
19(10):e0309449.
PMID: 39446792
COVID-19 convalescent plasma (CCP) was one of the first therapies to receive emergency use authorization for management of COVID-19. We assessed the effectiveness of CCP in a propensity-matched analysis, and...
3.
Nguyen Q, Rao K, Sembrat J, St Croix C, Kaufman B, Scott I, et al.
J Mol Cell Cardiol
. 2024 Apr;
190:79-81.
PMID: 38608599
No abstract available.
4.
DeVallance E, Dustin C, de Jesus D, Al Ghouleh I, Sembrat J, Cifuentes-Pagano E, et al.
Antioxidants (Basel)
. 2023 Jan;
12(1).
PMID: 36670936
Pulmonary arterial hypertension (PAH) is a rare yet devastating and incurable disease with few treatment options. The underlying mechanisms of PAH appear to involve substantial cellular proliferation and vascular remodeling,...
5.
Das A, Wang X, Wei J, Hoji A, Coon T, Popescu I, et al.
J Immunol
. 2022 Sep;
209(9):1788-1795.
PMID: 36113884
Chronic lung allograft dysfunction is the major barrier to long-term survival in lung transplant recipients. Evidence supports type 1 alloimmunity as the predominant response in acute/chronic lung rejection, but the...
6.
Popescu I, Snyder M, Iasella C, Hannan S, Koshy R, Burke R, et al.
Am J Respir Crit Care Med
. 2022 Mar;
205(12):1403-1418.
PMID: 35348444
Lymphopenia is common in severe coronavirus disease (COVID-19), yet the immune mechanisms are poorly understood. As inflammatory cytokines are increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, we...
7.
Li X, Lai Y, Lane Z, Strollo H, Tanimura K, Sembrat J, et al.
Thorax
. 2022 Mar;
78(4):402-408.
PMID: 35301243
Background: Birt-Hogg-Dubé syndrome (BHD) is a clinical syndrome manifesting with cystic lung disease and pneumothorax. Features of BHD result from the loss-of-function mutations of the folliculin () gene. Chronic obstructive...
8.
Manning J, Thapa D, Zhang M, Stoner M, Sembrat J, Rojas M, et al.
Am J Physiol Heart Circ Physiol
. 2022 Mar;
322(5):H762-H768.
PMID: 35245133
Reversible lysine acetylation regulates the activity of cardiac metabolic enzymes, including those controlling fuel substrate metabolism. Mitochondrial-targeted GCN5L1 and SIRT3 have been shown to regulate the acetylation status of mitochondrial...
9.
Clerk A, Meijles D, Hardyman M, Fuller S, Chothani S, Cull J, et al.
Biochem J
. 2022 Feb;
479(3):401-424.
PMID: 35147166
The extracellular signal-regulated kinase 1/2 (ERK1/2) cascade promotes cardiomyocyte hypertrophy and is cardioprotective, with the three RAF kinases forming a node for signal integration. Our aims were to determine if...
10.
Hages N, Sembrat J, Weber L, Johnston D, Stetten A, Sauleda M, et al.
J Aerosol Med Pulm Drug Deliv
. 2021 Oct;
35(3):146-153.
PMID: 34647795
Inhaled drug delivery can be limited by heterogeneous dose distribution. An additive that would disperse drug over the internal surfaces of the lung after aerosol deposition could improve dosing uniformity...