John C H Spence
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Explore the profile of John C H Spence including associated specialties, affiliations and a list of published articles.
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104
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4234
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Recent Articles
11.
Nagaratnam N, Tang Y, Botha S, Saul J, Li C, Hu H, et al.
Acta Crystallogr F Struct Biol Commun
. 2020 Jun;
76(Pt 6):278-289.
PMID: 32510469
μNS is a 70 kDa major nonstructural protein of avian reoviruses, which cause significant economic losses in the poultry industry. They replicate inside viral factories in host cells, and the...
12.
Gisriel C, Coe J, Letrun R, Yefanov O, Luna-Chavez C, Stander N, et al.
Nat Commun
. 2020 Feb;
11(1):703.
PMID: 32001708
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
13.
Gisriel C, Coe J, Letrun R, Yefanov O, Luna-Chavez C, Stander N, et al.
Nat Commun
. 2019 Nov;
10(1):5021.
PMID: 31685819
The world's first superconducting megahertz repetition rate hard X-ray free-electron laser (XFEL), the European XFEL, began operation in 2017, featuring a unique pulse train structure with 886 ns between pulses....
14.
Martin-Garcia J, Zhu L, Mendez D, Lee M, Chun E, Li C, et al.
IUCrJ
. 2019 May;
6(Pt 3):412-425.
PMID: 31098022
Since the first successful serial crystallography (SX) experiment at a synchrotron radiation source, the popularity of this approach has continued to grow showing that third-generation synchrotrons can be viable alternatives...
15.
Ishigami I, Lewis-Ballester A, Echelmeier A, Brehm G, Zatsepin N, Grant T, et al.
Proc Natl Acad Sci U S A
. 2019 Feb;
116(9):3572-3577.
PMID: 30808749
Cytochrome oxidase (CO) reduces dioxygen to water and harnesses the chemical energy to drive proton translocation across the inner mitochondrial membrane by an unresolved mechanism. By using time-resolved serial femtosecond...
16.
Li C, Li X, Kirian R, Spence J, Liu H, Zatsepin N
IUCrJ
. 2019 Feb;
6(Pt 1):72-84.
PMID: 30713705
(sparse-pattern indexing) is an auto-indexing algorithm for sparse snapshot diffraction patterns ('stills') that requires the positions of only five Bragg peaks in a single pattern, when provided with unit-cell parameters....
17.
Woitowich N, Halavaty A, Waltz P, Kupitz C, Valera J, Tracy G, et al.
IUCrJ
. 2018 Sep;
5(Pt 5):619-634.
PMID: 30224965
Phytochromes are red-light photoreceptors that were first characterized in plants, with homologs in photosynthetic and non-photosynthetic bacteria known as bacteriophytochromes (BphPs). Upon absorption of light, BphPs interconvert between two states...
18.
Arnal R, Zhao Y, Mitra A, Spence J, Millane R
Acta Crystallogr A Found Adv
. 2018 Sep;
74(Pt 5):537-544.
PMID: 30182940
Phasing of diffraction data from two-dimensional crystals using only minimal molecular envelope information is investigated by simulation. Two-dimensional crystals are an attractive target for studying membrane proteins using X-ray free-electron...
19.
Spence J
IUCrJ
. 2018 May;
5(Pt 3):236-237.
PMID: 29755740
Recent advances in the application of X-ray lasers to structural biology are providing time-resolved high-resolution imaging of many processes, from enzyme kinetics to the riboswitch in action, drug action, and...
20.
Li X, Spence J, Hogue B, Liu H
IUCrJ
. 2017 Nov;
4(Pt 6):741-750.
PMID: 29123676
X-ray free-electron lasers (XFELs) provide new opportunities for structure determination of biomolecules, viruses and nanomaterials. With unprecedented peak brilliance and ultra-short pulse duration, XFELs can tolerate higher X-ray doses by...